A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES

A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES

Tyramine sulfamate was linked to the trityl chloride resin and this polymeric support used to introduce two levels of molecular diversity by formation of peptide bonds. A dual cleavage strategy next generated in a sequential way (without resin split) two types of compounds (phenol and arylsulfamate...

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Bibliographic Details
Main Authors: Diane Fournier, Liviu Ciobanu, Donald Poirier
Format: Article
Language:English
Published: Academy of Sciences of Moldova, Institute of Chemistry 2015-12-01
Series:Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
Subjects:
solid-phase synthesis
linker
sulfamate
phenol
library
Online Access:http://www.cjm.asm.md/sites/default/files/article_files/ChemJMold201510(2)_68-76_Poirier.pdf
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spelling doaj-7c145ec16cba4a18a64a7dddaf92abc52021-07-02T06:09:41ZengAcademy of Sciences of Moldova, Institute of ChemistryChemistry Journal of Moldova: General, Industrial and Ecological Chemistry1857-17272345-16882015-12-011026876A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVESDiane Fournier0Liviu Ciobanu1Donald Poirier2Laboratory of Medicinal Chemistry, CHU de Québec – Research Center (CHUL, T4), 2705 Laurier Boulevard, Québec (Québec), G1V 4G2, CanadaLaboratory of Medicinal Chemistry, CHU de Québec – Research Center (CHUL, T4), 2705 Laurier Boulevard, Québec (Québec), G1V 4G2, CanadaLaboratory of Medicinal Chemistry, CHU de Québec – Research Center (CHUL, T4), 2705 Laurier Boulevard, Québec (Québec), G1V 4G2, CanadaTyramine sulfamate was linked to the trityl chloride resin and this polymeric support used to introduce two levels of molecular diversity by formation of peptide bonds. A dual cleavage strategy next generated in a sequential way (without resin split) two types of compounds (phenol and arylsulfamate derivatives), which are therapeutically attractive types of compounds.http://www.cjm.asm.md/sites/default/files/article_files/ChemJMold201510(2)_68-76_Poirier.pdfsolid-phase synthesislinkersulfamatephenollibrary
collection DOAJ
language English
format Article
sources DOAJ
author Diane Fournier
Liviu Ciobanu
Donald Poirier
spellingShingle Diane Fournier
Liviu Ciobanu
Donald Poirier
A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
solid-phase synthesis
linker
sulfamate
phenol
library
author_facet Diane Fournier
Liviu Ciobanu
Donald Poirier
author_sort Diane Fournier
title A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES
title_short A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES
title_full A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES
title_fullStr A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES
title_full_unstemmed A SEQUENTIAL DUAL CLEAVAGE OF THE ARYLSULFAMATE LINKER TO PROVIDE BOTH SULFAMATE AND PHENOL DERIVATIVES
title_sort sequential dual cleavage of the arylsulfamate linker to provide both sulfamate and phenol derivatives
publisher Academy of Sciences of Moldova, Institute of Chemistry
series Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
issn 1857-1727
2345-1688
publishDate 2015-12-01
description Tyramine sulfamate was linked to the trityl chloride resin and this polymeric support used to introduce two levels of molecular diversity by formation of peptide bonds. A dual cleavage strategy next generated in a sequential way (without resin split) two types of compounds (phenol and arylsulfamate derivatives), which are therapeutically attractive types of compounds.
topic solid-phase synthesis
linker
sulfamate
phenol
library
url http://www.cjm.asm.md/sites/default/files/article_files/ChemJMold201510(2)_68-76_Poirier.pdf
work_keys_str_mv AT dianefournier asequentialdualcleavageofthearylsulfamatelinkertoprovidebothsulfamateandphenolderivatives
AT liviuciobanu asequentialdualcleavageofthearylsulfamatelinkertoprovidebothsulfamateandphenolderivatives
AT donaldpoirier asequentialdualcleavageofthearylsulfamatelinkertoprovidebothsulfamateandphenolderivatives
AT dianefournier sequentialdualcleavageofthearylsulfamatelinkertoprovidebothsulfamateandphenolderivatives
AT liviuciobanu sequentialdualcleavageofthearylsulfamatelinkertoprovidebothsulfamateandphenolderivatives
AT donaldpoirier sequentialdualcleavageofthearylsulfamatelinkertoprovidebothsulfamateandphenolderivatives
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