Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report
Background: Inhibitory low frequency repetitive transcranial magnetic stimulation (rTMS) of the temporo-parietal area has been applied to treat both auditory verbal hallucinations as well as tinnitus. Objective: We hypothesized that 1 Hz rTMS to the left temporoparietal junction (TPJ) may be benefic...
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doaj-7c202031f286458a9633d9ea4565e1b62021-10-07T04:24:47ZengElsevierBrain Stimulation1935-861X2021-11-0114614671469Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case reportJanne Nordberg0Tero Taiminen1Lauri Virtanen2Satu K. Jääskeläinen3Noora M. Scheinin4Corresponding author. Department of Clinical Neurophysiology Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.; Department of Clinical Neurophysiology, University of Turku and Turku University Hospital, Turku, FinlandDepartment of Psychiatry, University of Turku and Turku University Hospital, Turku, FinlandDepartment of Psychiatry, University of Turku and Turku University Hospital, Turku, FinlandDepartment of Clinical Neurophysiology, University of Turku and Turku University Hospital, Turku, FinlandDepartment of Psychiatry, University of Turku and Turku University Hospital, Turku, FinlandBackground: Inhibitory low frequency repetitive transcranial magnetic stimulation (rTMS) of the temporo-parietal area has been applied to treat both auditory verbal hallucinations as well as tinnitus. Objective: We hypothesized that 1 Hz rTMS to the left temporoparietal junction (TPJ) may be beneficial in alleviating musical hallucinations (MH), another condition with auditory experiences in the absence of an external source. Methods: Here we describe a patient with almost insufferable life-long MH with comorbid depression, who received inhibitory rTMS to the left TPJ as well as the right dorsolateral prefrontal cortex (DLPFC). Results: The intrusiveness and frequency of her MH as well as her depressive symptoms alleviated quickly and substantially, and once-a-week maintenance therapy with rTMS seemed to preserve this amelioration. Future studies will hopefully reveal whether this is a viable treatment approach for other patients suffering from MH with or without comorbid depression.http://www.sciencedirect.com/science/article/pii/S1935861X21002412Musical hallucinationsrTMSTemporo-parietal junction |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Janne Nordberg Tero Taiminen Lauri Virtanen Satu K. Jääskeläinen Noora M. Scheinin |
spellingShingle |
Janne Nordberg Tero Taiminen Lauri Virtanen Satu K. Jääskeläinen Noora M. Scheinin Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report Brain Stimulation Musical hallucinations rTMS Temporo-parietal junction |
author_facet |
Janne Nordberg Tero Taiminen Lauri Virtanen Satu K. Jääskeläinen Noora M. Scheinin |
author_sort |
Janne Nordberg |
title |
Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report |
title_short |
Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report |
title_full |
Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report |
title_fullStr |
Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report |
title_full_unstemmed |
Successful suppression of musical hallucinations with low-frequency rTMS of the left temporo-parietal junction: A case report |
title_sort |
successful suppression of musical hallucinations with low-frequency rtms of the left temporo-parietal junction: a case report |
publisher |
Elsevier |
series |
Brain Stimulation |
issn |
1935-861X |
publishDate |
2021-11-01 |
description |
Background: Inhibitory low frequency repetitive transcranial magnetic stimulation (rTMS) of the temporo-parietal area has been applied to treat both auditory verbal hallucinations as well as tinnitus. Objective: We hypothesized that 1 Hz rTMS to the left temporoparietal junction (TPJ) may be beneficial in alleviating musical hallucinations (MH), another condition with auditory experiences in the absence of an external source. Methods: Here we describe a patient with almost insufferable life-long MH with comorbid depression, who received inhibitory rTMS to the left TPJ as well as the right dorsolateral prefrontal cortex (DLPFC). Results: The intrusiveness and frequency of her MH as well as her depressive symptoms alleviated quickly and substantially, and once-a-week maintenance therapy with rTMS seemed to preserve this amelioration. Future studies will hopefully reveal whether this is a viable treatment approach for other patients suffering from MH with or without comorbid depression. |
topic |
Musical hallucinations rTMS Temporo-parietal junction |
url |
http://www.sciencedirect.com/science/article/pii/S1935861X21002412 |
work_keys_str_mv |
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1716839987013484544 |