Quinacetophenone: A simple precursor to privileged organic motifs

This review presents the chemistry of quinacetophenone and its utility as an easily accessible building block for the synthesis of various advantageous organic compounds. This versatile precursor can be easily synthesized via different synthetic methodologies such as Friedel–Crafts acetylation, Frie...

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Main Authors: El-Sayed Ibrahim El-Desoky, Mohamed Ahmed Abozeid, Abdel-Rahman Hassan Abdel-Rahman
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535215002968
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spelling doaj-7c24c980a15d468abc86edf28b1c38da2020-11-25T02:45:28ZengElsevierArabian Journal of Chemistry1878-53522019-12-0112833803405Quinacetophenone: A simple precursor to privileged organic motifsEl-Sayed Ibrahim El-Desoky0Mohamed Ahmed Abozeid1Abdel-Rahman Hassan Abdel-Rahman2Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, EgyptCorresponding author. Tel.: +20 1004385945; fax: +20 502246254.; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, EgyptDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, EgyptThis review presents the chemistry of quinacetophenone and its utility as an easily accessible building block for the synthesis of various advantageous organic compounds. This versatile precursor can be easily synthesized via different synthetic methodologies such as Friedel–Crafts acetylation, Fries rearrangement and Hoesch reaction. Based upon its inherent chemical reactivity, the title compound has been utilized to construct various organic molecules such as chalcones, chromones, flavonoids, coumarins, quinones and azoles including various naturally and biologically active compounds. Keywords: Hydroxyacetophenone, Chalcone, Chromone, Flavone, Chromanone, Coumarinhttp://www.sciencedirect.com/science/article/pii/S1878535215002968
collection DOAJ
language English
format Article
sources DOAJ
author El-Sayed Ibrahim El-Desoky
Mohamed Ahmed Abozeid
Abdel-Rahman Hassan Abdel-Rahman
spellingShingle El-Sayed Ibrahim El-Desoky
Mohamed Ahmed Abozeid
Abdel-Rahman Hassan Abdel-Rahman
Quinacetophenone: A simple precursor to privileged organic motifs
Arabian Journal of Chemistry
author_facet El-Sayed Ibrahim El-Desoky
Mohamed Ahmed Abozeid
Abdel-Rahman Hassan Abdel-Rahman
author_sort El-Sayed Ibrahim El-Desoky
title Quinacetophenone: A simple precursor to privileged organic motifs
title_short Quinacetophenone: A simple precursor to privileged organic motifs
title_full Quinacetophenone: A simple precursor to privileged organic motifs
title_fullStr Quinacetophenone: A simple precursor to privileged organic motifs
title_full_unstemmed Quinacetophenone: A simple precursor to privileged organic motifs
title_sort quinacetophenone: a simple precursor to privileged organic motifs
publisher Elsevier
series Arabian Journal of Chemistry
issn 1878-5352
publishDate 2019-12-01
description This review presents the chemistry of quinacetophenone and its utility as an easily accessible building block for the synthesis of various advantageous organic compounds. This versatile precursor can be easily synthesized via different synthetic methodologies such as Friedel–Crafts acetylation, Fries rearrangement and Hoesch reaction. Based upon its inherent chemical reactivity, the title compound has been utilized to construct various organic molecules such as chalcones, chromones, flavonoids, coumarins, quinones and azoles including various naturally and biologically active compounds. Keywords: Hydroxyacetophenone, Chalcone, Chromone, Flavone, Chromanone, Coumarin
url http://www.sciencedirect.com/science/article/pii/S1878535215002968
work_keys_str_mv AT elsayedibrahimeldesoky quinacetophenoneasimpleprecursortoprivilegedorganicmotifs
AT mohamedahmedabozeid quinacetophenoneasimpleprecursortoprivilegedorganicmotifs
AT abdelrahmanhassanabdelrahman quinacetophenoneasimpleprecursortoprivilegedorganicmotifs
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