Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case
Fibrothecoma accounts for 3-4% of all ovarian neoplasms; it is usually hormonally inactive, but can be estrogenic or sometimes androgenic (11%); it is rare under 30 years. In a very few cases, minor sex cord elements (less than 10% of the tumor area) are present; therefore, it is considered as a sep...
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doaj-7c4719bf28f440a5a54100a5e9efb9612021-01-02T10:35:19ZengMDPI AGPediatric Reports2036-749X2036-75032014-08-016310.4081/pr.2014.54472888Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare caseNeelam Sood0Jitendra Singh Nigam1Geetika Goyal2Reeta Ranjan3Department of Pathology, Deen Dayal Upadhyay Hospital, Hari Nagar, New DelhiDepartment of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur, UPDepartment of Pathology, Deen Dayal Upadhyay Hospital, Hari Nagar, New DelhiDepartment of Obstetric And Gynecology, Deen Dayal Upadhyay Hospital, Hari Nagar, New DelhiFibrothecoma accounts for 3-4% of all ovarian neoplasms; it is usually hormonally inactive, but can be estrogenic or sometimes androgenic (11%); it is rare under 30 years. In a very few cases, minor sex cord elements (less than 10% of the tumor area) are present; therefore, it is considered as a separate sub-group of stromal tumors. The importance of immunohistochemistry in recognizing this kind of tumor has been fully documented, with variable results on inhibin staining, but specific positivity for calretenin in such cases. We report here the rare case of a 13-year-old child with ovarian fibrothecoma and minor sex cord stromal elements, who showed negativity for inhibin and positivity for calretenin.http://www.pagepress.org/journals/index.php/pr/article/view/5447estrogenic, immunohistochemistry, inhibin, calretenin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Neelam Sood Jitendra Singh Nigam Geetika Goyal Reeta Ranjan |
spellingShingle |
Neelam Sood Jitendra Singh Nigam Geetika Goyal Reeta Ranjan Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case Pediatric Reports estrogenic, immunohistochemistry, inhibin, calretenin |
author_facet |
Neelam Sood Jitendra Singh Nigam Geetika Goyal Reeta Ranjan |
author_sort |
Neelam Sood |
title |
Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case |
title_short |
Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case |
title_full |
Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case |
title_fullStr |
Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case |
title_full_unstemmed |
Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case |
title_sort |
virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case |
publisher |
MDPI AG |
series |
Pediatric Reports |
issn |
2036-749X 2036-7503 |
publishDate |
2014-08-01 |
description |
Fibrothecoma accounts for 3-4% of all ovarian neoplasms; it is usually hormonally inactive, but can be estrogenic or sometimes androgenic (11%); it is rare under 30 years. In a very few cases, minor sex cord elements (less than 10% of the tumor area) are present; therefore, it is considered as a separate sub-group of stromal tumors. The importance of immunohistochemistry in recognizing this kind of tumor has been fully documented, with variable results on inhibin staining, but specific positivity for calretenin in such cases. We report here the rare case of a 13-year-old child with ovarian fibrothecoma and minor sex cord stromal elements, who showed negativity for inhibin and positivity for calretenin. |
topic |
estrogenic, immunohistochemistry, inhibin, calretenin |
url |
http://www.pagepress.org/journals/index.php/pr/article/view/5447 |
work_keys_str_mv |
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