Emerging optofluidic technologies for biodiagnostic applications

Abstract The unprecedented global COVID‐19 pandemic strongly argues the critical need for innovative diagnostic tools meeting the requirement of test speed, accuracy, and throughput. Owing to the integration of optics and microfluidics technologies, optofluidic technology enables highly precise flow...

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Bibliographic Details
Main Authors: Jiandong Wu, Bo Dai, Zhenqing Li, Tingrui Pan, Dawei Zhang, Francis Lin
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:View
Subjects:
Online Access:https://doi.org/10.1002/VIW.20200035
Description
Summary:Abstract The unprecedented global COVID‐19 pandemic strongly argues the critical need for innovative diagnostic tools meeting the requirement of test speed, accuracy, and throughput. Owing to the integration of optics and microfluidics technologies, optofluidic technology enables highly precise flow manipulation and highly sensitive signal detection at the microscale, thus offering the promising potential for developing biodiagnostic applications. Research toward this direction is fast growing into an emerging area. In this paper, we give an overview of emerging optofluidic technologies for biodiagnostic applications with the focus on three common types of biomarkers: nucleic acid, protein, and cell. We conclude by discussing the challenges, opportunities, and future perspectives of this field.
ISSN:2688-3988
2688-268X