Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates
Prior studies have reported that separation anxiety disorder (SEPAD) can continue into or may begin in adulthood. Association of SEPAD with other psychiatric disorders has been frequently examined, and high rates of comorbidities have been found. The aim of this study was to investigate the prevalen...
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doaj-7c78793b18ad40c69657393617f7d2d72021-01-20T04:10:21ZengElsevierComprehensive Psychiatry0010-440X2021-02-01105152219Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlatesRümeysa Yeni Elbay0Aynur Görmez1Alperen Kılıç2Selma Hilal Avcı3Istanbul Medeniyet University, Faculty of Medicine, Psychiatry Department, Turkey; Corresponding author at: İstanbul Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi, Merdivenköy Poliklinikleri, Merdivenköy Mahallesi, Ressam Salih Ermez Cd. No:14, Kadıköy, İstanbul, Turkey.Istanbul Medeniyet University, Faculty of Medicine, Psychiatry Department, Istanbul Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi, Merdivenköy Poliklinikleri, Merdivenköy Mahallesi, Ressam Salih Ermez Cd. No:14, Kadıköy, İstanbul, TurkeyIstanbul Medipol University, Faculty of Medicine, Psychiatry Department, TEM Avrupa Otoyolu Göztepe Çıkışı No:1, 34214 Bağcılar, İstanbul, TurkeyIstanbul Medeniyet University, Faculty of Medicine, Psychiatry Department, İstanbul Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi, Merdivenköy Poliklinikleri, Merdivenköy Mahallesi, Ressam Salih Ermez Cd. No:14, Kadıköy, İstanbul, TurkeyPrior studies have reported that separation anxiety disorder (SEPAD) can continue into or may begin in adulthood. Association of SEPAD with other psychiatric disorders has been frequently examined, and high rates of comorbidities have been found. The aim of this study was to investigate the prevalence and clinical correlation of SEPAD in adult patients undergoing treatment for major depressive disorder (MDD). The study sample was comprised of 100 outpatients. Participants underwent a DSM-5-based comprehensive assessment. Purposefully-designed semi-structured sociodemographic information and illness history forms were filled out by the researchers, and diagnoses of SEPAD were made using the Structured Clinical Interview for Separation Anxiety Symptoms, Separation Anxiety Symptom Inventory and Adult Separation Anxiety Survey. The frequency of SEPAD was 41% in patients with MDD, three-quarters of whom were adult onset. The use of new-generation antidepressants, adjunctive medications and comorbidity of other anxiety disorders were higher in patients with SEPAD (p < 0.05). SEPAD was highly prevalent, with a majority of cases starting in adulthood among patients with MDD, while SEPAD comorbidity was associated with high levels of anxiety and an increased likelihood of suboptimal response to usual depression treatment. Further studies are required to define the relevance and pathological basis for the comorbidity of SEPAD in people with MDD.http://www.sciencedirect.com/science/article/pii/S0010440X20300614ComorbidityDepressionPrevalenceSeparation anxiety |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rümeysa Yeni Elbay Aynur Görmez Alperen Kılıç Selma Hilal Avcı |
spellingShingle |
Rümeysa Yeni Elbay Aynur Görmez Alperen Kılıç Selma Hilal Avcı Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates Comprehensive Psychiatry Comorbidity Depression Prevalence Separation anxiety |
author_facet |
Rümeysa Yeni Elbay Aynur Görmez Alperen Kılıç Selma Hilal Avcı |
author_sort |
Rümeysa Yeni Elbay |
title |
Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates |
title_short |
Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates |
title_full |
Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates |
title_fullStr |
Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates |
title_full_unstemmed |
Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates |
title_sort |
separation anxiety disorder among outpatients with major depressive disorder: prevalence and clinical correlates |
publisher |
Elsevier |
series |
Comprehensive Psychiatry |
issn |
0010-440X |
publishDate |
2021-02-01 |
description |
Prior studies have reported that separation anxiety disorder (SEPAD) can continue into or may begin in adulthood. Association of SEPAD with other psychiatric disorders has been frequently examined, and high rates of comorbidities have been found. The aim of this study was to investigate the prevalence and clinical correlation of SEPAD in adult patients undergoing treatment for major depressive disorder (MDD). The study sample was comprised of 100 outpatients. Participants underwent a DSM-5-based comprehensive assessment. Purposefully-designed semi-structured sociodemographic information and illness history forms were filled out by the researchers, and diagnoses of SEPAD were made using the Structured Clinical Interview for Separation Anxiety Symptoms, Separation Anxiety Symptom Inventory and Adult Separation Anxiety Survey. The frequency of SEPAD was 41% in patients with MDD, three-quarters of whom were adult onset. The use of new-generation antidepressants, adjunctive medications and comorbidity of other anxiety disorders were higher in patients with SEPAD (p < 0.05). SEPAD was highly prevalent, with a majority of cases starting in adulthood among patients with MDD, while SEPAD comorbidity was associated with high levels of anxiety and an increased likelihood of suboptimal response to usual depression treatment. Further studies are required to define the relevance and pathological basis for the comorbidity of SEPAD in people with MDD. |
topic |
Comorbidity Depression Prevalence Separation anxiety |
url |
http://www.sciencedirect.com/science/article/pii/S0010440X20300614 |
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