Baicalein Mediates Mitochondrial Autophagy via miR-30b and the NIX/BNIP3 Signaling Pathway in Parkinson’s Disease
Parkinson’s disease (PD) is regarded as a severe neurodegenerative disorder. Baicalein is involved in the treatment of PD. This study explored the mechanism of baicalein in PD. The PD rat model was established using 6-hydroxydopamine. The neurologic score, dopamine (DA) content, apoptotic cells, and...
Main Authors: | Min Chen, Li Peng, Ping Gong, Xiaoli Zheng, Tao Sun, Xiaoqiao Zhang, Jiangtao Huo |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2021-01-01
|
Series: | Biochemistry Research International |
Online Access: | http://dx.doi.org/10.1155/2021/2319412 |
Similar Items
-
Potential Roles of NIX/BNIP3L Pathway in Rat Traumatic Brain Injury
by: Jialing Ma, et al.
Published: (2019-05-01) -
BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria.
by: Yasuyuki Nakamura, et al.
Published: (2012-01-01) -
The role of KLHL23 in BNIP3L/NIX -mediated mitophagy in Hepatocellular Carcinoma
by: Yu Chen Hung, et al.
Published: (2016) -
BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects
by: Gee Euhn Choi, et al.
Published: (2021-01-01) -
Autophagy and BNIP3 protein in tumorogenesis
by: Ewelina Świderek, et al.
Published: (2013-05-01)