Nocardia veterana infections: case report and systematic review
Members of the genus Nocardia are filamentous, Gram-positive, aerobic bacteria and exist ubiquitously in most environments. In 2001, the species Nocardia veterana was first isolated, and it predominantly causes pulmonary infections in immunocompromised hosts. We present the first report of a soft-ti...
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doaj-7c7ea0346e92435bacac63564132f12c2021-01-22T04:49:44ZengElsevierNew Microbes and New Infections2052-29752021-01-0139100833Nocardia veterana infections: case report and systematic reviewC. Radcliffe0D. Peaper1M. Grant2Yale School of Medicine, New Haven, CT, USA; Corresponding author: C. Radcliffe, Yale Infectious Diseases, PO Box 208022, New Haven, CT, 06520, USA.Yale School of Medicine, New Haven, CT, USA; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USAYale School of Medicine, New Haven, CT, USA; Department of Internal Medicine, Section of Infectious Diseases, Yale New Haven Hospital, New Haven, CT, USAMembers of the genus Nocardia are filamentous, Gram-positive, aerobic bacteria and exist ubiquitously in most environments. In 2001, the species Nocardia veterana was first isolated, and it predominantly causes pulmonary infections in immunocompromised hosts. We present the first report of a soft-tissue abscess caused by N. veterana in a 59-year-old woman being treated for chronic cutaneous graft-versus-host disease. After failing to improve with empirical treatment, two incision and drainage procedures were required. She subsequently completed a 1-year course of oral antibiotic therapy consisting of trimethoprim-sulfamethoxazole then azithromycin. No relapse occurred over the next 5 years of follow up. To better characterize N. veterana infections, we performed a systematic literature review and summarized all previously reported cases. Overall, the rising prevalence of immunocompromising conditions warrants increased vigilance for infections caused by atypical or opportunistic pathogens.http://www.sciencedirect.com/science/article/pii/S2052297520301852Abscessgraft-versus-host diseaseNocardia veterananocardiosistrimethoprim-sulfamethoxazole |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
C. Radcliffe D. Peaper M. Grant |
spellingShingle |
C. Radcliffe D. Peaper M. Grant Nocardia veterana infections: case report and systematic review New Microbes and New Infections Abscess graft-versus-host disease Nocardia veterana nocardiosis trimethoprim-sulfamethoxazole |
author_facet |
C. Radcliffe D. Peaper M. Grant |
author_sort |
C. Radcliffe |
title |
Nocardia veterana infections: case report and systematic review |
title_short |
Nocardia veterana infections: case report and systematic review |
title_full |
Nocardia veterana infections: case report and systematic review |
title_fullStr |
Nocardia veterana infections: case report and systematic review |
title_full_unstemmed |
Nocardia veterana infections: case report and systematic review |
title_sort |
nocardia veterana infections: case report and systematic review |
publisher |
Elsevier |
series |
New Microbes and New Infections |
issn |
2052-2975 |
publishDate |
2021-01-01 |
description |
Members of the genus Nocardia are filamentous, Gram-positive, aerobic bacteria and exist ubiquitously in most environments. In 2001, the species Nocardia veterana was first isolated, and it predominantly causes pulmonary infections in immunocompromised hosts. We present the first report of a soft-tissue abscess caused by N. veterana in a 59-year-old woman being treated for chronic cutaneous graft-versus-host disease. After failing to improve with empirical treatment, two incision and drainage procedures were required. She subsequently completed a 1-year course of oral antibiotic therapy consisting of trimethoprim-sulfamethoxazole then azithromycin. No relapse occurred over the next 5 years of follow up. To better characterize N. veterana infections, we performed a systematic literature review and summarized all previously reported cases. Overall, the rising prevalence of immunocompromising conditions warrants increased vigilance for infections caused by atypical or opportunistic pathogens. |
topic |
Abscess graft-versus-host disease Nocardia veterana nocardiosis trimethoprim-sulfamethoxazole |
url |
http://www.sciencedirect.com/science/article/pii/S2052297520301852 |
work_keys_str_mv |
AT cradcliffe nocardiaveteranainfectionscasereportandsystematicreview AT dpeaper nocardiaveteranainfectionscasereportandsystematicreview AT mgrant nocardiaveteranainfectionscasereportandsystematicreview |
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