An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells.

Current efforts to develop HIV vaccines that seek to stimulate immune responses have been disappointing, underscoring the inability of natural immune responses to control HIV-1 infection. Here we tested an alternative strategy to induce anti-HIV immune responses by inhibiting a host's natural i...

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Bibliographic Details
Main Authors: Xiao-Tong Song, Kevin Evel-Kabler, Lisa Rollins, Melissa Aldrich, Feng Gao, Xue F Huang, Si-Yi Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1323501?pdf=render