Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
Plasmodium actins form very short filaments and have a noncanonical link between ATP hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the structural factors constraining Plasmodium microfilament lengths have remained unknown. Using high-resolution crystallography,...
Main Authors: | Esa-Pekka Kumpula, Andrea J Lopez, Leila Tajedin, Huijong Han, Inari Kursula |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-06-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000315 |
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