| Summary: | The interaction of hafnium(IV) salts (oxide-dichloride, chloride, and bromide) with nitrilotriacetic acid (NTA), diethylenetriamminepentaacetic acid (DTPA), 1,2-diaminocyclohexanetetraacetic acid (CDTA), 1,3-dipropylmino-2-hydroxy <i>N</i>,<i>N</i>,<i>N</i>′,<i>N</i>′-tetraacetic acid (dpta), and <i>N</i>-(2-hydroxyethyl)ethylenediamine triacetic acid (HEDTA) has been studied. The corresponding complexes Na<sub>2</sub>[Hf(NTA)<sub>2</sub>]·3H<sub>2</sub>O (<b>1</b>), Na[HfDTPA]·3H<sub>2</sub>O (<b>2</b>), [HfCDTA(H<sub>2</sub>O)<sub>2</sub>] (<b>3</b>), and Na[Hf<sub>2</sub>(dpta)<sub>2</sub>]·7.5H<sub>2</sub>O·0.5C<sub>2</sub>H<sub>5</sub>OH (<b>4</b>) have been isolated and characterized and their structures have been determined by single crystal X-ray diffraction. Biological studies of [HfCDTA(H<sub>2</sub>O)<sub>2</sub>] have shown that in 5% glucose solution this complex has low toxicity and good contrasting ability.
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