MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

MicroRNA and mRNA profiling in the idiopathic inflammatory myopathies

Abstract Background The idiopathic inflammatory myopathies (IIMs) are heterogeneous autoimmune conditions of skeletal muscle inflammation and weakness. MicroRNAs (miRNAs) are short, non-coding RNA which regulate gene expression of target mRNAs. The aim of this study was to profile miRNA and mRNA in...

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Bibliographic Details
Main Authors: Joanna E. Parkes, Anastasia Thoma, Adam P. Lightfoot, Philip J. Day, Hector Chinoy, Janine A. Lamb
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Rheumatology
Subjects:
Idiopathic inflammatory myopathies
Polymyositis
Dermatomyositis
microRNA
RNA sequencing
Online Access:http://link.springer.com/article/10.1186/s41927-020-00125-8

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