Influence of levofloxacin on soluble selection, interleukin, adhesion molecule and pulmonary surfactant protein of patients with pulmonary tuberculosis

• Main Authors: Qing-Zhou He, Qian-Shu Hu
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2016-04-01
• Series: Journal of Hainan Medical University
• Subjects: Qian-Shu Hu; Levofloxacin; Pulmonary tuberculosis; Soluble selection; Interleukin; Adhesion molecule; Pulmonary surfactant protein
• Online Access: http://www.hnykdxxb.com/PDF/201607/9.pdf

Objective: To observe the influence of levofloxacin on soluble selection, interleukin, adhesion molecule and pulmonary surfactant protein of patients with pulmonary tuberculosis. Methods: A total of 50 patients with pulmonary tuberculosis who had been treated in our hospital from March 2014 to April 2015 were randomly divided into the control group (conventional treatment) and the observation group (conventional treatment plus levofloxacin). Each group had 25 cases. Then, the soluble selection，interleukin，adhesion molecule and pulmonary surfactant protein levels of the two groups at the second, fourth and sixth months before and after treatment were compared. Results: Before treatment, the differencess of the levels of the soluble selection, interleukin, adhesion molecule and pulmonary surfactant protein of the two groups were significant (P>0.05), while the detection levels of all the aspects of the observation group at the second, fourth and sixth months after treatment were all significantly lower than those of the control group (P<0.05). The detection results of the two groups at the second, fourth and sixth months after treatment showed significant differences. Conclusions: Lvofloxacin has significant effect on the soluble selection, interleukin, adhesion molecule and pulmonary surfactant protein of patients with pulmonary tuberculosis.