Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
Boron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers. Clinical interest in BNCT focuses in neuro-oncology on therapy for gliomas, glioblastoma in particular, and BNCT may b...
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doaj-7ccf132ca9a74f03a05ee5c5ef37bcbe2021-09-15T15:32:22ZengLUCHEVAYA DIAGNOSTIKA, LLCВестник рентгенологии и радиологии0042-46762619-04782016-03-0106364210.20862/0042-4676-2015-0-6-142-14291Possibilities of boron neutron capture therapy in the treatment of malignant brain tumorsV. V. Kanygin0A. I. Kichigin1N. V. Gubanova2S. Yu Taskaev3Novosibirsk State Medical University, Ministry of Health of the RF, G.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Road Clinical Hospital Station Novosibirsk-Main Open Joint Stock Company «Russian Railways»G.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Road Clinical Hospital Station Novosibirsk-Main Open Joint Stock Company «Russian Railways»G.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk State University National ResearchG.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk State University National ResearchBoron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers. Clinical interest in BNCT focuses in neuro-oncology on therapy for gliomas, glioblastoma in particular, and BNCT may be used in brain metastatic involvement. This needs an epithermal neutron source that complies with the requirements for BNCT, as wellas a 10B-containing agent that will selectively accumulate in tumor tissue. The introduction of BNCT into clinical practice to treat patients with glial tumors will be able to enhance therapeutic efficiency.https://www.russianradiology.ru/jour/article/view/91boron neutron capture therapyglioblastomaneutron sources |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
V. V. Kanygin A. I. Kichigin N. V. Gubanova S. Yu Taskaev |
spellingShingle |
V. V. Kanygin A. I. Kichigin N. V. Gubanova S. Yu Taskaev Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors Вестник рентгенологии и радиологии boron neutron capture therapy glioblastoma neutron sources |
author_facet |
V. V. Kanygin A. I. Kichigin N. V. Gubanova S. Yu Taskaev |
author_sort |
V. V. Kanygin |
title |
Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors |
title_short |
Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors |
title_full |
Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors |
title_fullStr |
Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors |
title_full_unstemmed |
Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors |
title_sort |
possibilities of boron neutron capture therapy in the treatment of malignant brain tumors |
publisher |
LUCHEVAYA DIAGNOSTIKA, LLC |
series |
Вестник рентгенологии и радиологии |
issn |
0042-4676 2619-0478 |
publishDate |
2016-03-01 |
description |
Boron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers. Clinical interest in BNCT focuses in neuro-oncology on therapy for gliomas, glioblastoma in particular, and BNCT may be used in brain metastatic involvement. This needs an epithermal neutron source that complies with the requirements for BNCT, as wellas a 10B-containing agent that will selectively accumulate in tumor tissue. The introduction of BNCT into clinical practice to treat patients with glial tumors will be able to enhance therapeutic efficiency. |
topic |
boron neutron capture therapy glioblastoma neutron sources |
url |
https://www.russianradiology.ru/jour/article/view/91 |
work_keys_str_mv |
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1717378760584462336 |