Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors

Boron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers. Clinical interest in BNCT focuses in neuro-oncology on therapy for gliomas, glioblastoma in particular, and BNCT may b...

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Main Authors: V. V. Kanygin, A. I. Kichigin, N. V. Gubanova, S. Yu Taskaev
Format: Article
Language:English
Published: LUCHEVAYA DIAGNOSTIKA, LLC 2016-03-01
Series:Вестник рентгенологии и радиологии
Subjects:
Online Access:https://www.russianradiology.ru/jour/article/view/91
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spelling doaj-7ccf132ca9a74f03a05ee5c5ef37bcbe2021-09-15T15:32:22ZengLUCHEVAYA DIAGNOSTIKA, LLCВестник рентгенологии и радиологии0042-46762619-04782016-03-0106364210.20862/0042-4676-2015-0-6-142-14291Possibilities of boron neutron capture therapy in the treatment of malignant brain tumorsV. V. Kanygin0A. I. Kichigin1N. V. Gubanova2S. Yu Taskaev3Novosibirsk State Medical University, Ministry of Health of the RF, G.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Road Clinical Hospital Station Novosibirsk-Main Open Joint Stock Company «Russian Railways»G.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Road Clinical Hospital Station Novosibirsk-Main Open Joint Stock Company «Russian Railways»G.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk State University National ResearchG.I. Budker Institute of Nuclear Physics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk State University National ResearchBoron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers. Clinical interest in BNCT focuses in neuro-oncology on therapy for gliomas, glioblastoma in particular, and BNCT may be used in brain metastatic involvement. This needs an epithermal neutron source that complies with the requirements for BNCT, as wellas a 10B-containing agent that will selectively accumulate in tumor tissue. The introduction of BNCT into clinical practice to treat patients with glial tumors will be able to enhance therapeutic efficiency.https://www.russianradiology.ru/jour/article/view/91boron neutron capture therapyglioblastomaneutron sources
collection DOAJ
language English
format Article
sources DOAJ
author V. V. Kanygin
A. I. Kichigin
N. V. Gubanova
S. Yu Taskaev
spellingShingle V. V. Kanygin
A. I. Kichigin
N. V. Gubanova
S. Yu Taskaev
Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
Вестник рентгенологии и радиологии
boron neutron capture therapy
glioblastoma
neutron sources
author_facet V. V. Kanygin
A. I. Kichigin
N. V. Gubanova
S. Yu Taskaev
author_sort V. V. Kanygin
title Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
title_short Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
title_full Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
title_fullStr Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
title_full_unstemmed Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
title_sort possibilities of boron neutron capture therapy in the treatment of malignant brain tumors
publisher LUCHEVAYA DIAGNOSTIKA, LLC
series Вестник рентгенологии и радиологии
issn 0042-4676
2619-0478
publishDate 2016-03-01
description Boron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers. Clinical interest in BNCT focuses in neuro-oncology on therapy for gliomas, glioblastoma in particular, and BNCT may be used in brain metastatic involvement. This needs an epithermal neutron source that complies with the requirements for BNCT, as wellas a 10B-containing agent that will selectively accumulate in tumor tissue. The introduction of BNCT into clinical practice to treat patients with glial tumors will be able to enhance therapeutic efficiency.
topic boron neutron capture therapy
glioblastoma
neutron sources
url https://www.russianradiology.ru/jour/article/view/91
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AT aikichigin possibilitiesofboronneutroncapturetherapyinthetreatmentofmalignantbraintumors
AT nvgubanova possibilitiesofboronneutroncapturetherapyinthetreatmentofmalignantbraintumors
AT syutaskaev possibilitiesofboronneutroncapturetherapyinthetreatmentofmalignantbraintumors
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