Heat stress induces apoptosis through a Ca²⁺-mediated mitochondrial apoptotic pathway in human umbilical vein endothelial cells.

Heat stress induces apoptosis through a Ca²⁺-mediated mitochondrial apoptotic pathway in human umbilical vein endothelial cells.

Heat stress can be acutely cytotoxic, and heat stress-induced apoptosis is a prominent pathological feature of heat-related illnesses, although the precise mechanisms by which heat stress triggers apoptosis are poorly defined.The percentages of viability and cell death were assessed by WST-1 and LDH...

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Bibliographic Details
Main Authors: Li Li, Hongping Tan, Zhengtao Gu, Zhifeng Liu, Yan Geng, Yunsong Liu, Huasheng Tong, Youqing Tang, Junmin Qiu, Lei Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280109?pdf=render

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