Pharmacogenetics of proton pump inhibitors
Proton pump inhibitors (PPI) are currently the most effective class of antisecretory drugs widely used in the treatment of non-ulcer dyspepsia, reflux esophagitis and GERD, peptic ulcer disease and H. pilory infection, as well as NSAID-associated gastric lesions. Despite the common mechanism of acti...
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Remedium Group LLC
2015-12-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/433 |
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doaj-7cfd404e358b4c21bbd3ad0daa4d73fe2021-07-28T13:29:22ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902015-12-010179610310.21518/2079-701X-2015-17-96-103433Pharmacogenetics of proton pump inhibitorsM. V. Leonova0Russian Medical Research University named after N.I. PirogovProton pump inhibitors (PPI) are currently the most effective class of antisecretory drugs widely used in the treatment of non-ulcer dyspepsia, reflux esophagitis and GERD, peptic ulcer disease and H. pilory infection, as well as NSAID-associated gastric lesions. Despite the common mechanism of action and pharmacological effects of this class of drugs, there is clinical inter-individual variability of their effect on acid production determined by pharmacokinetic and pharmacogenetic factors. As a result, the clinical efficacy of treatment of acid-base disorders and eradication of H. pilory is decreased.https://www.med-sovet.pro/jour/article/view/433ингибиторы протонной помпыэрадикационная терапияproton pump inhibitorseradication therapy |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
M. V. Leonova |
| spellingShingle |
M. V. Leonova Pharmacogenetics of proton pump inhibitors Медицинский совет ингибиторы протонной помпы эрадикационная терапия proton pump inhibitors eradication therapy |
| author_facet |
M. V. Leonova |
| author_sort |
M. V. Leonova |
| title |
Pharmacogenetics of proton pump inhibitors |
| title_short |
Pharmacogenetics of proton pump inhibitors |
| title_full |
Pharmacogenetics of proton pump inhibitors |
| title_fullStr |
Pharmacogenetics of proton pump inhibitors |
| title_full_unstemmed |
Pharmacogenetics of proton pump inhibitors |
| title_sort |
pharmacogenetics of proton pump inhibitors |
| publisher |
Remedium Group LLC |
| series |
Медицинский совет |
| issn |
2079-701X 2658-5790 |
| publishDate |
2015-12-01 |
| description |
Proton pump inhibitors (PPI) are currently the most effective class of antisecretory drugs widely used in the treatment of non-ulcer dyspepsia, reflux esophagitis and GERD, peptic ulcer disease and H. pilory infection, as well as NSAID-associated gastric lesions. Despite the common mechanism of action and pharmacological effects of this class of drugs, there is clinical inter-individual variability of their effect on acid production determined by pharmacokinetic and pharmacogenetic factors. As a result, the clinical efficacy of treatment of acid-base disorders and eradication of H. pilory is decreased. |
| topic |
ингибиторы протонной помпы эрадикационная терапия proton pump inhibitors eradication therapy |
| url |
https://www.med-sovet.pro/jour/article/view/433 |
| work_keys_str_mv |
AT mvleonova pharmacogeneticsofprotonpumpinhibitors |
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