Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study
The evidence for the association between diurnal temperature range (DTR) and diabetic foot amputations is limited. We aimed to investigate the region-specific association between DTR and the amputation rate of diabetic foot in Korean national-wide data. Daily data on DTR and the rate of diabetic foo...
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doaj-7d00cb04f50d4e54b1c212628423f6032021-09-09T13:45:28ZengMDPI AGInternational Journal of Environmental Research and Public Health1661-78271660-46012021-08-01189191919110.3390/ijerph18179191Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide StudySung Hun Won0Hyung-Jin Chung1Jinyoung Lee2Ye Jin Jeon3Dong-Il Chun4Tae-Hong Min5Jaeho Cho6Sungho Won7Young Yi8Department of Orthopedic Surgery, Soon Chun Hyang University Seoul Hospital, Seoul 04401, KoreaDepartment of Orthopedic Surgery, Inje University Sanggye Paik Hospital, Seoul 01757, KoreaDepartment of Statistics, Chung-Ang University, Seoul 06974, KoreaRexSoft Corps, Seoul 08826, KoreaDepartment of Orthopedic Surgery, Soon Chun Hyang University Seoul Hospital, Seoul 04401, KoreaDepartment of Orthopedic Surgery, Soon Chun Hyang University Seoul Hospital, Seoul 04401, KoreaDepartment of Orthopaedic Surgery, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 24253, KoreaRexSoft Corps, Seoul 08826, KoreaDepartment of Orthopedic Surgery, Inje University Seoul Paik Hospital, Seoul 04551, KoreaThe evidence for the association between diurnal temperature range (DTR) and diabetic foot amputations is limited. We aimed to investigate the region-specific association between DTR and the amputation rate of diabetic foot in Korean national-wide data. Daily data on DTR and the rate of diabetic foot amputations from 16 provincial capital cities in Korea were obtained (2011–2018). In this study, the latitude ranged from 33°11′ N to 38°61′ N, and we classified each region according to latitude. Region 1, which was located at a relatively high latitude, included Seoul, Incheon, Gyeonggi-do, and Gangwon-do. Region 2, which was located at a relatively low latitude, included Busan, Ulsan, Gyeonsannam-do, Gwangju, Jeollanam-do, Jeollabuk-do, and Jeju-do. The region-specific DTR effects on the amputation rate were estimated based on a quasi-Poisson generalized linear model, combined with a distributed lag non-linear model based on the self-controlled case series design. The DTR impacts were generally limited to a period of nine days, while significant effects during lag days 7–14 were only found in the cities of Seoul, Incheon, and Gyeonggi-do (10th lag day: RR [95% CI]; Seoul: 1.015, [1.001–1.029]; Incheon: 1.052 [1.006–1.101]; Gyeonggi-do: 1.018 [1.002–1.034]). In the subgroup analysis (according to the latitude), an increase of 1 °C in DTR was associated with the risk of diabetic foot in relatively high latitude regions. DTR has considerable effects on the risk of diabetic foot amputation in various provinces in Korea, and it was particularly affected by latitude. The results can inform the decisions on developing programs to protect vulnerable subpopulations from adverse impacts.https://www.mdpi.com/1660-4601/18/17/9191diabetic footdiabetic peripheral neuritisdiurnal temperature rangeamputation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sung Hun Won Hyung-Jin Chung Jinyoung Lee Ye Jin Jeon Dong-Il Chun Tae-Hong Min Jaeho Cho Sungho Won Young Yi |
spellingShingle |
Sung Hun Won Hyung-Jin Chung Jinyoung Lee Ye Jin Jeon Dong-Il Chun Tae-Hong Min Jaeho Cho Sungho Won Young Yi Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study International Journal of Environmental Research and Public Health diabetic foot diabetic peripheral neuritis diurnal temperature range amputation |
author_facet |
Sung Hun Won Hyung-Jin Chung Jinyoung Lee Ye Jin Jeon Dong-Il Chun Tae-Hong Min Jaeho Cho Sungho Won Young Yi |
author_sort |
Sung Hun Won |
title |
Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study |
title_short |
Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study |
title_full |
Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study |
title_fullStr |
Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study |
title_full_unstemmed |
Diurnal Temperature Ranges in Relation to Lower Limb Amputation Rate of Diabetic Foot in South Korea: A Population Based Nationwide Study |
title_sort |
diurnal temperature ranges in relation to lower limb amputation rate of diabetic foot in south korea: a population based nationwide study |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1661-7827 1660-4601 |
publishDate |
2021-08-01 |
description |
The evidence for the association between diurnal temperature range (DTR) and diabetic foot amputations is limited. We aimed to investigate the region-specific association between DTR and the amputation rate of diabetic foot in Korean national-wide data. Daily data on DTR and the rate of diabetic foot amputations from 16 provincial capital cities in Korea were obtained (2011–2018). In this study, the latitude ranged from 33°11′ N to 38°61′ N, and we classified each region according to latitude. Region 1, which was located at a relatively high latitude, included Seoul, Incheon, Gyeonggi-do, and Gangwon-do. Region 2, which was located at a relatively low latitude, included Busan, Ulsan, Gyeonsannam-do, Gwangju, Jeollanam-do, Jeollabuk-do, and Jeju-do. The region-specific DTR effects on the amputation rate were estimated based on a quasi-Poisson generalized linear model, combined with a distributed lag non-linear model based on the self-controlled case series design. The DTR impacts were generally limited to a period of nine days, while significant effects during lag days 7–14 were only found in the cities of Seoul, Incheon, and Gyeonggi-do (10th lag day: RR [95% CI]; Seoul: 1.015, [1.001–1.029]; Incheon: 1.052 [1.006–1.101]; Gyeonggi-do: 1.018 [1.002–1.034]). In the subgroup analysis (according to the latitude), an increase of 1 °C in DTR was associated with the risk of diabetic foot in relatively high latitude regions. DTR has considerable effects on the risk of diabetic foot amputation in various provinces in Korea, and it was particularly affected by latitude. The results can inform the decisions on developing programs to protect vulnerable subpopulations from adverse impacts. |
topic |
diabetic foot diabetic peripheral neuritis diurnal temperature range amputation |
url |
https://www.mdpi.com/1660-4601/18/17/9191 |
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