Is sickle cell disease-related neurotoxicity a systemic endotheliopathy?

The aim of the present article is to review the role of endothelial damage and dysfunction in the vaso-occlusive episodes associated with sickle cell disease (SCD). This inherited hematological disorder leads to irreversible damage of multiple organs through a wide variety of mechanisms, such as sic...

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Bibliographic Details
Main Authors: Marta Palomo, Maribel Diaz-Ricart, Enric Carreras
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
SCD
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387620300224