MITOCHONDRIAL HAPLOGROUPS DEFINE TWO PHENOTYPES OF OSTEOARTHRITIS

MITOCHONDRIAL HAPLOGROUPS DEFINE TWO PHENOTYPES OF OSTEOARTHRITIS

Objective. To assess a mitochondrion-related phenotype in patients with osteoarthritis (OA).Methods. Serum levels of the following OA-related biomarkers: matrix metalloproteinase-1 (MMP-1); MMP-3; MMP-13; myeloperoxidase (MPO); a peptide of the alpha-helical region of type II collagen, Coll2-1, and...

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Bibliographic Details
Main Authors: Mercedes eFernandez-Moreno, Angel eHermida-Soto, Natividad eOreiro, Carlos eFernandez-Lopez, Sonia ePertega, Ignacio eRego-Perez, Francisco J eBlanco
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Physiology
Subjects:
Genes
Mitochondria
Osteoarthritis
haplogroups
phenotypes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00129/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00129/full

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