PD-L1 and PD-1 expression are correlated with distinctive clinicopathological features in papillary thyroid carcinoma

PD-L1 and PD-1 expression are correlated with distinctive clinicopathological features in papillary thyroid carcinoma

Abstract Background Immune checkpoint blockade targeting PD-1/PD-L1 has shown efficacy in several types of cancers. However, the correlation between PD-L1/PD-1 expression and the specific clinicopathological features in papillary thyroid carcinoma (PTC) has not been investigated. Methods We examined...

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Bibliographic Details
Main Authors: Yanhua Bai, Dongfeng Niu, Xiaozheng Huang, Ling Jia, Qiang Kang, Fangyuan Dou, Xinqiang Ji, Weicheng Xue, Yiqiang Liu, Zhongwu Li, Qin Feng, Dongmei Lin, Kennichi Kakudo
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Diagnostic Pathology
Subjects:
BRAF V600E
Chronic lymphocytic thyroiditis
Papillary thyroid carcinoma
PD-1
PD-L1
Tumor-infiltrating lymphocytes
Online Access:http://link.springer.com/article/10.1186/s13000-017-0662-z

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