An Overview of Fotemustine in High-Grade Gliomas: From Single Agent to Association with Bevacizumab

Fotemustine is a third-generation nitrosourea showing efficacy in various types of tumors such as melanoma and glioma. We reviewed the most important studies on fotemustine treatment in glioma patients analyzing its pharmacological profile and its activity and safety. Fotemustine was used as single...

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Bibliographic Details
Main Authors: Giuseppe Lombardi, Patrizia Farina, Alessandro Della Puppa, Diego Cecchin, Ardi Pambuku, Luisa Bellu, Vittorina Zagonel
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/698542