APOE2 is associated with spatial navigational strategies and increased grey matter in the hippocampus

The Apolipoprotein E (APOE) gene has a strong association with Alzheimer’s disease (AD). The ε4 allele is a well-documented genetic risk factor of AD. In contrast, the ε2 allele of the APOE gene is known to be protective against AD. Much of the focus on the APOE gene has been on the ε4 allele in bot...

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Bibliographic Details
Main Authors: Kyoko Konishi, Venkat Bhat, Harrison Banner, Judes Poirier, Ridha Joober, Veronique D Bohbot
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00349/full