Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching
Antibody class switching is a feature of the adaptive immune system which enables diversification of the effector properties of antibodies. Even though class switching is essential for mounting a protective response to pathogens, the in vivo patterns and lineage characteristics of antibody class swi...
Main Authors: | Felix Horns, Christopher Vollmers, Derek Croote, Sally F Mackey, Gary E Swan, Cornelia L Dekker, Mark M Davis, Stephen R Quake |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/16578 |
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