Mitochondrial Dysfunction in Neural Injury

Mitochondrial Dysfunction in Neural Injury

Mitochondria are the double membrane organelles providing most of the energy for cells. In addition, mitochondria also play essential roles in various cellular biological processes such as calcium signaling, apoptosis, ROS generation, cell growth, and cell cycle. Mitochondrial dysfunction is observe...

Full description

Bibliographic Details
Main Authors: Xiu-Yun Zhao, Mei-Hong Lu, De-Juan Yuan, De-En Xu, Pei-Pei Yao, Wen-Li Ji, Hong Chen, Wen-Long Liu, Chen-Xiao Yan, Yi-Yuan Xia, Shao Li, Jin Tao, Quan-Hong Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroscience
Subjects:
mitochondrial dysfunction
neural injury
mitochondria
neurodegeneration
neurological disorders
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00030/full
Description
Summary:Mitochondria are the double membrane organelles providing most of the energy for cells. In addition, mitochondria also play essential roles in various cellular biological processes such as calcium signaling, apoptosis, ROS generation, cell growth, and cell cycle. Mitochondrial dysfunction is observed in various neurological disorders which harbor acute and chronic neural injury such as neurodegenerative diseases and ischemia, hypoxia-induced brain injury. In this review, we describe how mitochondrial dysfunction contributes to the pathogenesis of neurological disorders which manifest chronic or acute neural injury.
ISSN:1662-453X

Similar Items