MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis

MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis

Receptor interacting protein kinase 3 (RIPK3)-mediated smooth muscle cell (SMC) necroptosis has been shown to contribute to the pathogenesis of abdominal aortic aneurysms (AAAs). However, the signaling steps downstream from RIPK3 during SMC necroptosis remain unknown. In this study, the roles of mix...

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Bibliographic Details
Main Authors: Ting Zhou, Elise DeRoo, Huan Yang, Amelia Stranz, Qiwei Wang, Roman Ginnan, Harold A. Singer, Bo Liu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
necroptosis
smooth muscle cells
MLKL
CaMKII
abdominal aortic aneurysm
Online Access:https://www.mdpi.com/2073-4409/10/9/2397

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