Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials

The review presents a clinical expert meta-analysis of compliance with the basic requirements for safety and efficacy Of subunit influenza vaccine containing polymer Polyoxidonium (PO) as an adjuvant (PO-AG). The results of the meta-analysis convincingly demonstrate that a reduced HA dose in combina...

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Main Author:	R. Kompier
Format:	Article
Language:	Russian
Published:	Numikom LLC 2018-09-01
Series:	Эпидемиология и вакцинопрофилактика
Subjects:	influenza vaccine grippol polyoxidonium
Online Access:	https://www.epidemvac.ru/jour/article/view/564

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spelling	doaj-7d8ee7dc8291498a94298be1b66885a42021-07-28T13:31:50ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942018-09-011749298458Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical TrialsR. Kompier0European consulting biotechnology company FluconsultThe review presents a clinical expert meta-analysis of compliance with the basic requirements for safety and efficacy Of subunit influenza vaccine containing polymer Polyoxidonium (PO) as an adjuvant (PO-AG). The results of the meta-analysis convincingly demonstrate that a reduced HA dose in combination with the adjuvant PO is safe and low reactogenic and induces a humoral immune response comparable to that of other inactivated vaccines without adjuvant. PO-AG is safe and effective vaccine against influenza.https://www.epidemvac.ru/jour/article/view/564influenzavaccinegrippolpolyoxidonium
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	R. Kompier
spellingShingle	R. Kompier Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials Эпидемиология и вакцинопрофилактика influenza vaccine grippol polyoxidonium
author_facet	R. Kompier
author_sort	R. Kompier
title	Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials
title_short	Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials
title_full	Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials
title_fullStr	Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials
title_full_unstemmed	Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials
title_sort	safety and efficacy of a subunit vaccine against flu containing polyoxidonium systematic review and meta-analysis of clinical trials
publisher	Numikom LLC
series	Эпидемиология и вакцинопрофилактика
issn	2073-3046 2619-0494
publishDate	2018-09-01
description	The review presents a clinical expert meta-analysis of compliance with the basic requirements for safety and efficacy Of subunit influenza vaccine containing polymer Polyoxidonium (PO) as an adjuvant (PO-AG). The results of the meta-analysis convincingly demonstrate that a reduced HA dose in combination with the adjuvant PO is safe and low reactogenic and induces a humoral immune response comparable to that of other inactivated vaccines without adjuvant. PO-AG is safe and effective vaccine against influenza.
topic	influenza vaccine grippol polyoxidonium
url	https://www.epidemvac.ru/jour/article/view/564
work_keys_str_mv	AT rkompier safetyandefficacyofasubunitvaccineagainstflucontainingpolyoxidoniumsystematicreviewandmetaanalysisofclinicaltrials
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Safety and Efficacy of a Subunit Vaccine against Flu Containing Polyoxidonium Systematic Review and Meta-Analysis of Clinical Trials

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