Non-Enzymatic Glucose Biosensor Based on Highly Pure TiO<sub>2</sub> Nanoparticles
This study proposes a non-enzymatic glucose sensor fabricated by synthesizing high-purity TiO<sub>2</sub> nanoparticles in thermal plasma and depositing it directly on a substrate and then depositing chitosan–polypyrrole (CS-PPy) conductive polymer films by electrochemical method. The st...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
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Series: | Biosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6374/11/5/149 |
Summary: | This study proposes a non-enzymatic glucose sensor fabricated by synthesizing high-purity TiO<sub>2</sub> nanoparticles in thermal plasma and depositing it directly on a substrate and then depositing chitosan–polypyrrole (CS-PPy) conductive polymer films by electrochemical method. The structural properties of the deposited TiO<sub>2</sub> nanoparticles were analyzed by X-ray diffraction (XRD) and dynamic light scattering (DLS) system. The chemical composition and structural properties of the TiO<sub>2</sub> nanoparticle layer and the conductive polymer films were confirmed by X-ray photoelectron spectroscopy (XPS) spectra and scanning electron microscope (SEM). The glucose detection characteristics of the fabricated biosensor were determined by cyclic voltammetry (CV). CS-PPy/TiO<sub>2</sub> biosensor showed high sensitivity of 302.0 µA mM<sup>−1</sup> cm<sup>−2</sup> (<i>R</i><sup>2</sup> = 0.9957) and low detection limit of 6.7 μM. The easily manufactured CS-PPy/TiO<sub>2</sub> biosensor showed excellent selectivity and reactivity. |
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ISSN: | 2079-6374 |