Penalized partial least squares for pleiotropy
Abstract Background The increasing number of genome-wide association studies (GWAS) has revealed several loci that are associated to multiple distinct phenotypes, suggesting the existence of pleiotropic effects. Highlighting these cross-phenotype genetic associations could help to identify and under...
Main Authors: | Camilo Broc, Therese Truong, Benoit Liquet |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-03968-1 |
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