Cell-free propagation of Coxiella burnetii does not affect its relative virulence.
Q fever is caused by the obligate intracellular bacterium Coxiella burnetii. In vitro growth of the bacterium is usually limited to viable eukaryotic host cells imposing experimental constraints for molecular studies, such as the identification and characterisation of major virulence factors. Studie...
Main Authors: | Runa Kuley, Hilde E Smith, Dimitrios Frangoulidis, Mari A Smits, Hendrik I Jan Roest, Alex Bossers |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0121661 |
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