Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK
Aims: This study explores the reported rate of surgical site infection (SSI) after hip fracture surgery in published studies concerning patients treated in the UK. Methods: Studies were included if they reported on SSI after any type of surgical treatment for hip fracture. Each study required a mini...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The British Editorial Society of Bone & Joint Surgery
2020-09-01
|
Series: | Bone & Joint Research |
Subjects: | |
Online Access: | https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2020-0023.R1 |
id |
doaj-7dbcf2992ac1463c841fdc00d5801082 |
---|---|
record_format |
Article |
spelling |
doaj-7dbcf2992ac1463c841fdc00d58010822020-11-25T03:41:52ZengThe British Editorial Society of Bone & Joint SurgeryBone & Joint Research2046-37582020-09-019955456210.1302/2046-3758.99.BJR-2020-0023.R1Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UKJames Masters0David Metcalfe1Joon Soo Ha2Andrew Judge3Matthew L. Costa4Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UKNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UKThe Royal College of Surgeons of England, London, UKNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UKOxford Trauma, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UKAims: This study explores the reported rate of surgical site infection (SSI) after hip fracture surgery in published studies concerning patients treated in the UK. Methods: Studies were included if they reported on SSI after any type of surgical treatment for hip fracture. Each study required a minimum of 30 days follow-up and 100 patients. Meta-analysis was undertaken using a random effects model. Heterogeneity was expressed using the I2 statistic. Risk of bias was assessed using a modified Newcastle-Ottawa Scale (NOS) system. Results: There were 20 studies reporting data from 88,615 patients. Most were retrospective cohort studies from single centres. The pooled incidence was 2.1% (95% confidence interval (CI) 1.54% to 2.62%) across ‘all types’ of hip fracture surgery. When analyzed by operation type, the SSI incidences were: hemiarthroplasty 2.87% (95% CI 1.99% to 3.75%) and sliding hip screw 1.35% (95% CI 0.78% to 1.93%). There was considerable variation in definition of infection used, as well as considerable risk of bias, particularly as few studies actively screened participants for SSI. Conclusion: Synthesis of published estimates of infection yield a rate higher than that seen in national surveillance procedures. Biases noted in all studies would trend towards an underestimate, largely due to inadequate follow-up.https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2020-0023.R1hip fracturesurgical site infectionepidemiology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
James Masters David Metcalfe Joon Soo Ha Andrew Judge Matthew L. Costa |
spellingShingle |
James Masters David Metcalfe Joon Soo Ha Andrew Judge Matthew L. Costa Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK Bone & Joint Research hip fracture surgical site infection epidemiology |
author_facet |
James Masters David Metcalfe Joon Soo Ha Andrew Judge Matthew L. Costa |
author_sort |
James Masters |
title |
Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK |
title_short |
Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK |
title_full |
Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK |
title_fullStr |
Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK |
title_full_unstemmed |
Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK |
title_sort |
surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the uk |
publisher |
The British Editorial Society of Bone & Joint Surgery |
series |
Bone & Joint Research |
issn |
2046-3758 |
publishDate |
2020-09-01 |
description |
Aims: This study explores the reported rate of surgical site infection (SSI) after hip fracture surgery in published studies concerning patients treated in the UK. Methods: Studies were included if they reported on SSI after any type of surgical treatment for hip fracture. Each study required a minimum of 30 days follow-up and 100 patients. Meta-analysis was undertaken using a random effects model. Heterogeneity was expressed using the I2 statistic. Risk of bias was assessed using a modified Newcastle-Ottawa Scale (NOS) system. Results: There were 20 studies reporting data from 88,615 patients. Most were retrospective cohort studies from single centres. The pooled incidence was 2.1% (95% confidence interval (CI) 1.54% to 2.62%) across ‘all types’ of hip fracture surgery. When analyzed by operation type, the SSI incidences were: hemiarthroplasty 2.87% (95% CI 1.99% to 3.75%) and sliding hip screw 1.35% (95% CI 0.78% to 1.93%). There was considerable variation in definition of infection used, as well as considerable risk of bias, particularly as few studies actively screened participants for SSI. Conclusion: Synthesis of published estimates of infection yield a rate higher than that seen in national surveillance procedures. Biases noted in all studies would trend towards an underestimate, largely due to inadequate follow-up. |
topic |
hip fracture surgical site infection epidemiology |
url |
https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2020-0023.R1 |
work_keys_str_mv |
AT jamesmasters surgicalsiteinfectionafterhipfracturesurgeryasystematicreviewandmetaanalysisofstudiespublishedintheuk AT davidmetcalfe surgicalsiteinfectionafterhipfracturesurgeryasystematicreviewandmetaanalysisofstudiespublishedintheuk AT joonsooha surgicalsiteinfectionafterhipfracturesurgeryasystematicreviewandmetaanalysisofstudiespublishedintheuk AT andrewjudge surgicalsiteinfectionafterhipfracturesurgeryasystematicreviewandmetaanalysisofstudiespublishedintheuk AT matthewlcosta surgicalsiteinfectionafterhipfracturesurgeryasystematicreviewandmetaanalysisofstudiespublishedintheuk |
_version_ |
1724527759038873600 |