Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus
This review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corre- sponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chr...
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doaj-7dcb73d0d09f4bd383cbb400c3b77b272021-06-02T19:41:36ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782013-06-01162364210.14341/2072-0351-37543724Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitusSergey Valentinovich Kakorin0Lev Borisovich Kruglyi1Ashot Musaelovich Mkrtumyan2City Hospital №4, MoscowI.M. Sechenov First Moscow State Medical University, MoscowMoscow State University of Medicine and Dentistry, MoscowThis review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corre- sponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chronic ischemic alterations in myocardium (the so-called ?metabolic ischemia?), as well as concomitant microangiopathy. It is more common for patients with T2DM to develop such complications of ACS as cardiogenic shock, acute left ventricular failure and arrhythmia that result in increased lethality during early hours of hospital admission when myocardial necrosis is yet to occur. Percutaneous translumenal intervention is by far the most effective method of ACS management in patients with T2DM. Whenever it is not available, a thrombolytic approach is indicated.https://dia-endojournals.ru/dia/article/viewFile/3754/1930type 2 diabetes mellitusacute coronary syndromemyocardial infarctionmetabolic ischemiamacroangiopathymicro- angiopathyrevascularization |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan |
spellingShingle |
Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus Сахарный диабет type 2 diabetes mellitus acute coronary syndrome myocardial infarction metabolic ischemia macroangiopathy micro- angiopathy revascularization |
author_facet |
Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan |
author_sort |
Sergey Valentinovich Kakorin |
title |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
title_short |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
title_full |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
title_fullStr |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
title_full_unstemmed |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
title_sort |
clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
publisher |
Endocrinology Research Centre |
series |
Сахарный диабет |
issn |
2072-0351 2072-0378 |
publishDate |
2013-06-01 |
description |
This review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corre- sponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chronic ischemic alterations in myocardium (the so-called ?metabolic ischemia?), as well as concomitant microangiopathy. It is more common for patients with T2DM to develop such complications of ACS as cardiogenic shock, acute left ventricular failure and arrhythmia that result in increased lethality during early hours of hospital admission when myocardial necrosis is yet to occur. Percutaneous translumenal intervention is by far the most effective method of ACS management in patients with T2DM. Whenever it is not available, a thrombolytic approach is indicated. |
topic |
type 2 diabetes mellitus acute coronary syndrome myocardial infarction metabolic ischemia macroangiopathy micro- angiopathy revascularization |
url |
https://dia-endojournals.ru/dia/article/viewFile/3754/1930 |
work_keys_str_mv |
AT sergeyvalentinovichkakorin clinicalandmorphologicalcharacteristicsmanagementandprognosisforacutecoronarysyndromeinpatientswithtype2diabetesmellitus AT levborisovichkruglyi clinicalandmorphologicalcharacteristicsmanagementandprognosisforacutecoronarysyndromeinpatientswithtype2diabetesmellitus AT ashotmusaelovichmkrtumyan clinicalandmorphologicalcharacteristicsmanagementandprognosisforacutecoronarysyndromeinpatientswithtype2diabetesmellitus |
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1721401390387953664 |