Experimental models of foamy macrophages and approaches for dissecting the mechanisms of lipid accumulation and consumption during dormancy and reactivation of tuberculosis

Experimental models of foamy macrophages and approaches for dissecting the mechanisms of lipid accumulation and consumption during dormancy and reactivation of tuberculosis

Despite a slight decline since 2014, tuberculosis (TB) remains the major most deadly infectious disease worldwide with about 1.5 million deaths each year and with about one-third of the population being latently infected with Mycobacterium tuberculosis, the etiologic agent of TB. During primo-infect...

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Bibliographic Details
Main Authors: Pierre Santucci, Feriel Bouzid, Nabil Smichi, Isabelle Poncin, Laurent Kremer, Chantal de Chastellier, Michel DRANCOURT, Stephane Canaan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Amoeba
Granuloma
Lipid Metabolism
Pathogenesis
mycobacteria
Adipocyte
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00122/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00122/full

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