Sweet taste receptor deficient mice have decreased adiposity and increased bone mass.

Functional expression of sweet taste receptors (T1R2 and T1R3) has been reported in numerous metabolic tissues, including the gut, pancreas, and, more recently, in adipose tissue. It has been suggested that sweet taste receptors in these non-gustatory tissues may play a role in systemic energy balan...

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Bibliographic Details
Main Authors: Becky R Simon, Brian S Learman, Sebastian D Parlee, Erica L Scheller, Hiroyuki Mori, William P Cawthorn, Xiaomin Ning, Venkatesh Krishnan, Yanfei L Ma, Björn Tyrberg, Ormond A MacDougald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899259?pdf=render