Sweet taste receptor deficient mice have decreased adiposity and increased bone mass.
Functional expression of sweet taste receptors (T1R2 and T1R3) has been reported in numerous metabolic tissues, including the gut, pancreas, and, more recently, in adipose tissue. It has been suggested that sweet taste receptors in these non-gustatory tissues may play a role in systemic energy balan...
Main Authors: | Becky R Simon, Brian S Learman, Sebastian D Parlee, Erica L Scheller, Hiroyuki Mori, William P Cawthorn, Xiaomin Ning, Venkatesh Krishnan, Yanfei L Ma, Björn Tyrberg, Ormond A MacDougald |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3899259?pdf=render |
Similar Items
-
Increased circulating adiponectin in response to thiazolidinediones: investigating the role of bone marrow adipose tissue
by: Richard J Sulston, et al.
Published: (2016-09-01) -
Adipose tissue stem cells meet preadipocyte commitment: going back to the future[S]
by: William P. Cawthorn, et al.
Published: (2012-02-01) -
Signaling Pathway Puts the Break on Fat Cell Formation
by: Ormond A. MacDougald
Published: (2001-01-01) -
Editorial: Bone Marrow Adipose Tissue: Formation, Function, and Impact on Health and Disease
by: William P. Cawthorn, et al.
Published: (2017-05-01) -
Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity.
by: Xiaoya Ma, et al.
Published: (2017-01-01)