A genome-wide assessment of the ancestral neural crest gene regulatory network

An understanding of the ancestral state of the neural crest (NC) gene regulatory network (GRN) gives insight into vertebrate evolution. Here, the authors use transcriptomic and chromatin accessibility analyses of the lamprey NC, as well as cross-species enhancer assays, to identify GRN elements cons...

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Main Authors:	Dorit Hockman, Vanessa Chong-Morrison, Stephen A. Green, Daria Gavriouchkina, Ivan Candido-Ferreira, Irving T. C. Ling, Ruth M. Williams, Chris T. Amemiya, Jeramiah J. Smith, Marianne E. Bronner, Tatjana Sauka-Spengler
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-12687-4

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spelling	doaj-7de47f5d63c1453fbb323ae97151c9b92021-05-11T11:28:53ZengNature Publishing GroupNature Communications2041-17232019-10-0110111510.1038/s41467-019-12687-4A genome-wide assessment of the ancestral neural crest gene regulatory networkDorit Hockman0Vanessa Chong-Morrison1Stephen A. Green2Daria Gavriouchkina3Ivan Candido-Ferreira4Irving T. C. Ling5Ruth M. Williams6Chris T. Amemiya7Jeramiah J. Smith8Marianne E. Bronner9Tatjana Sauka-Spengler10Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordRadcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordDivision of Biology and Biological Engineering, California Institute of TechnologyRadcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordRadcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordRadcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordRadcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordMolecular Cell Biology, School of Natural Sciences, University of CaliforniaDepartment of Biology, University of KentuckyDivision of Biology and Biological Engineering, California Institute of TechnologyRadcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of OxfordAn understanding of the ancestral state of the neural crest (NC) gene regulatory network (GRN) gives insight into vertebrate evolution. Here, the authors use transcriptomic and chromatin accessibility analyses of the lamprey NC, as well as cross-species enhancer assays, to identify GRN elements conserved throughout vertebrates.https://doi.org/10.1038/s41467-019-12687-4
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Dorit Hockman Vanessa Chong-Morrison Stephen A. Green Daria Gavriouchkina Ivan Candido-Ferreira Irving T. C. Ling Ruth M. Williams Chris T. Amemiya Jeramiah J. Smith Marianne E. Bronner Tatjana Sauka-Spengler
spellingShingle	Dorit Hockman Vanessa Chong-Morrison Stephen A. Green Daria Gavriouchkina Ivan Candido-Ferreira Irving T. C. Ling Ruth M. Williams Chris T. Amemiya Jeramiah J. Smith Marianne E. Bronner Tatjana Sauka-Spengler A genome-wide assessment of the ancestral neural crest gene regulatory network Nature Communications
author_facet	Dorit Hockman Vanessa Chong-Morrison Stephen A. Green Daria Gavriouchkina Ivan Candido-Ferreira Irving T. C. Ling Ruth M. Williams Chris T. Amemiya Jeramiah J. Smith Marianne E. Bronner Tatjana Sauka-Spengler
author_sort	Dorit Hockman
title	A genome-wide assessment of the ancestral neural crest gene regulatory network
title_short	A genome-wide assessment of the ancestral neural crest gene regulatory network
title_full	A genome-wide assessment of the ancestral neural crest gene regulatory network
title_fullStr	A genome-wide assessment of the ancestral neural crest gene regulatory network
title_full_unstemmed	A genome-wide assessment of the ancestral neural crest gene regulatory network
title_sort	genome-wide assessment of the ancestral neural crest gene regulatory network
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-10-01
description	An understanding of the ancestral state of the neural crest (NC) gene regulatory network (GRN) gives insight into vertebrate evolution. Here, the authors use transcriptomic and chromatin accessibility analyses of the lamprey NC, as well as cross-species enhancer assays, to identify GRN elements conserved throughout vertebrates.
url	https://doi.org/10.1038/s41467-019-12687-4
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A genome-wide assessment of the ancestral neural crest gene regulatory network

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