Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies
Background: Examination of bone marrow plays a pivotal role in the practice of haematology. It can be evaluated by three ways–bone marrow aspiration (BMA), bone marrow touch imprints (BMI) and bone marrow biopsy (BMBx). Aim and Objective: To study the efficacy and reliability of BMI smears in c...
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doaj-7def82a7cfcd48c094d387826ac2ecca2020-11-25T03:51:37ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-11-01811FC01FC0310.7860/JCDR/2014/9898.5127Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow PathologiesVijai Tilak0Subhajit Das1Soobashchan Bundhun2Associate Professor, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.Junior Resident, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.Junior Resident, Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.Background: Examination of bone marrow plays a pivotal role in the practice of haematology. It can be evaluated by three ways–bone marrow aspiration (BMA), bone marrow touch imprints (BMI) and bone marrow biopsy (BMBx). Aim and Objective: To study the efficacy and reliability of BMI smears in comparison to BMA smears, in making a diagnosis of diseases involving bone marrow. Setting and Designs: This study was carried out in the Department of Pathology, Institute of Medical Sciences, Varanasi over a period of 26 months. Materials and Methods: A total number of 182 cases, with their BMA, BMI and BMBx samples (from each and every case), were evaluated and their findings even compared. Statistical Analysis: All the observations were evaluated using simple and basic statistical tool, i.e. percentage. Results: The cellularity or cell density on BMI correlated with the cellularity of BMBx in 78.6% cases, which was higher than the value observed with BMA smears (71.4%). The spreading quality was better and cytological details were better appreciated in BMI as compared to BMA. Also, the presence of lymphoglandular bodies and particles on BMI were additive diagnostic clues. All of those findings were reflected in the higher diagnostic accuracy of BMI than BMA. Conclusion: BMI should be a standard practice and be considered as an early and reliable diagnostic tool for evaluating bone marrow pathologies.https://jcdr.net/articles/PDF/5127/9898_CE(Ra)_F(Sh)_PF1(AJ_Sh)_PFA(Sh)_PF2(PAG).pdfbone marrow aspiration(bma)bone marrow biopsy(bmbx)bone marrow imprint (bmi) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Vijai Tilak Subhajit Das Soobashchan Bundhun |
spellingShingle |
Vijai Tilak Subhajit Das Soobashchan Bundhun Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies Journal of Clinical and Diagnostic Research bone marrow aspiration(bma) bone marrow biopsy(bmbx) bone marrow imprint (bmi) |
author_facet |
Vijai Tilak Subhajit Das Soobashchan Bundhun |
author_sort |
Vijai Tilak |
title |
Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies |
title_short |
Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies |
title_full |
Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies |
title_fullStr |
Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies |
title_full_unstemmed |
Value of Bone Marrow Imprint Smears in Early Diagnosis Of Bone Marrow Pathologies |
title_sort |
value of bone marrow imprint smears in early diagnosis of bone marrow pathologies |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2014-11-01 |
description |
Background: Examination of bone marrow plays a pivotal role
in the practice of haematology. It can be evaluated by three
ways–bone marrow aspiration (BMA), bone marrow touch
imprints (BMI) and bone marrow biopsy (BMBx).
Aim and Objective: To study the efficacy and reliability of BMI
smears in comparison to BMA smears, in making a diagnosis of
diseases involving bone marrow.
Setting and Designs: This study was carried out in the
Department of Pathology, Institute of Medical Sciences,
Varanasi over a period of 26 months.
Materials and Methods: A total number of 182 cases, with
their BMA, BMI and BMBx samples (from each and every case),
were evaluated and their findings even compared.
Statistical Analysis: All the observations were evaluated using
simple and basic statistical tool, i.e. percentage.
Results: The cellularity or cell density on BMI correlated with
the cellularity of BMBx in 78.6% cases, which was higher
than the value observed with BMA smears (71.4%). The
spreading quality was better and cytological details were better
appreciated in BMI as compared to BMA. Also, the presence
of lymphoglandular bodies and particles on BMI were additive
diagnostic clues. All of those findings were reflected in the
higher diagnostic accuracy of BMI than BMA.
Conclusion: BMI should be a standard practice and be
considered as an early and reliable diagnostic tool for evaluating
bone marrow pathologies. |
topic |
bone marrow aspiration(bma) bone marrow biopsy(bmbx) bone marrow imprint (bmi) |
url |
https://jcdr.net/articles/PDF/5127/9898_CE(Ra)_F(Sh)_PF1(AJ_Sh)_PFA(Sh)_PF2(PAG).pdf |
work_keys_str_mv |
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