Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential
Small numbers of hematopoietic stem cells (HSCs) generate large numbers of mature effector cells through the successive amplification of transiently proliferating progenitor cells. HSCs and their downstream progenitors have been extensively characterized based on their cell-surface phenotype and fun...
Main Authors: | John W. Fathman, Nathaniel B. Fernhoff, Jun Seita, Connie Chao, Vanessa M. Scarfone, Irving L. Weissman, Matthew A. Inlay |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-11-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671114002926 |
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