O′Brien actinic granuloma: A case report and brief review of literature

• Main Authors: Inês D Coutinho, Leonor I C Ramos, Maria M Brites, Oscar Tellechea
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: Indian Journal of Dermatology
• Subjects: Annular elastolytic giant cell granuloma; elastophagocytosis; Miescher granuloma of the face; necrobiosis lipoidica presenting on the face and scalp; O′Brien actinic granuloma
• Online Access: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=4;spage=391;epage=393;aulast=Coutinho
• ISSN: 0019-5154; 1998-3611

O′Brien first described the actinic granuloma in 1975, as an infrequent granulomatous disorder occurring in sun-exposed skin, with a slow but often self-limited course. Ever since its initial description, the actinic physiopathogenic hypothesis has been debated by many authors. We report a 60-year-old female rural worker that presented with a 14 × 7 cm annular lesion with erythematous elevated borders and an atrophic center on the right calf. The lesion was evolving for 2 years, and histopathology confirmed actinic granuloma. She started acitretin with halting of disease progression after 6 months of therapy. Our case can also be associated to actinic damage, despite its unusual location, therefore highlighting the role of solar elastosis in the development of O′Brien actinic granuloma.