Neonatal hepatitis with herpes simplex

We report two cases of neonatal hepatitis with herpes simplex virus (HSV) infection. Whether the HSV infection was the cause of hepatitis, or merely associated with it is not clear. While, in the first case, resolution could not be achieved despite high-dose antiviral treatment with acyclovir and li...

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Main Authors: Rishika Sakaria, Ira Shah, Sushmita Bhatnagar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Medical Journal of Dr. D.Y. Patil University
Subjects:
Online Access:http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=3;spage=397;epage=399;aulast=Sakaria
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spelling doaj-7e1365c0ed584d55a55a6c902bd14bc22020-11-24T22:17:53ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil University0975-28702016-01-019339739910.4103/0975-2870.182521Neonatal hepatitis with herpes simplexRishika SakariaIra ShahSushmita BhatnagarWe report two cases of neonatal hepatitis with herpes simplex virus (HSV) infection. Whether the HSV infection was the cause of hepatitis, or merely associated with it is not clear. While, in the first case, resolution could not be achieved despite high-dose antiviral treatment with acyclovir and liver transplant had to be advised; in the second case, there was complete resolution of the disease without antiviral therapy. Role of acyclovir in these children needs further assessment.http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=3;spage=397;epage=399;aulast=SakariaAntiviral therapyherpes simplexneonateviral hepatitis
collection DOAJ
language English
format Article
sources DOAJ
author Rishika Sakaria
Ira Shah
Sushmita Bhatnagar
spellingShingle Rishika Sakaria
Ira Shah
Sushmita Bhatnagar
Neonatal hepatitis with herpes simplex
Medical Journal of Dr. D.Y. Patil University
Antiviral therapy
herpes simplex
neonate
viral hepatitis
author_facet Rishika Sakaria
Ira Shah
Sushmita Bhatnagar
author_sort Rishika Sakaria
title Neonatal hepatitis with herpes simplex
title_short Neonatal hepatitis with herpes simplex
title_full Neonatal hepatitis with herpes simplex
title_fullStr Neonatal hepatitis with herpes simplex
title_full_unstemmed Neonatal hepatitis with herpes simplex
title_sort neonatal hepatitis with herpes simplex
publisher Wolters Kluwer Medknow Publications
series Medical Journal of Dr. D.Y. Patil University
issn 0975-2870
publishDate 2016-01-01
description We report two cases of neonatal hepatitis with herpes simplex virus (HSV) infection. Whether the HSV infection was the cause of hepatitis, or merely associated with it is not clear. While, in the first case, resolution could not be achieved despite high-dose antiviral treatment with acyclovir and liver transplant had to be advised; in the second case, there was complete resolution of the disease without antiviral therapy. Role of acyclovir in these children needs further assessment.
topic Antiviral therapy
herpes simplex
neonate
viral hepatitis
url http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=3;spage=397;epage=399;aulast=Sakaria
work_keys_str_mv AT rishikasakaria neonatalhepatitiswithherpessimplex
AT irashah neonatalhepatitiswithherpessimplex
AT sushmitabhatnagar neonatalhepatitiswithherpessimplex
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