Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis
The article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomogra...
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NEW TERRA Publishing House
2020-11-01
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doaj-7e1a5b4a2fb247708602e3423019df472021-07-28T20:57:49ZrusNEW TERRA Publishing HouseTuberkulez i Bolezni Lëgkih2075-12302542-15062020-11-019810475110.21292/2075-1230-2020-98-10-47-511472Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosisM. E. Lozovskaya0Yu. A. Yarovaya1E. В. Vasilieva2L. N. Khamchieva3A. V. Mosina4P. V. Gavrilov5St. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversityChildren Infectious Hospital no. 3St. Petersburg Research Institute of PhthisiopulmonologyThe article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomography. The particular parameter of latent tuberculosis infection of this case was the positive results of IGRA tests (T-SPOT TB and QuantiFERON) with a negative response to the intradermal test with recombinant tuberculosis allergen. According to the examination results, the disseminated tuberculosis was not confirmed, diffuse lung damage was regarded as a manifestation of Gaucher disease, which was a rare sign of this pathology according to the published data.https://www.tibl-journal.com/jour/article/view/1474childrendisseminated lung damagegaucher diseasetuberculosisdifferential diagnosis |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
M. E. Lozovskaya Yu. A. Yarovaya E. В. Vasilieva L. N. Khamchieva A. V. Mosina P. V. Gavrilov |
spellingShingle |
M. E. Lozovskaya Yu. A. Yarovaya E. В. Vasilieva L. N. Khamchieva A. V. Mosina P. V. Gavrilov Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis Tuberkulez i Bolezni Lëgkih children disseminated lung damage gaucher disease tuberculosis differential diagnosis |
author_facet |
M. E. Lozovskaya Yu. A. Yarovaya E. В. Vasilieva L. N. Khamchieva A. V. Mosina P. V. Gavrilov |
author_sort |
M. E. Lozovskaya |
title |
Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis |
title_short |
Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis |
title_full |
Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis |
title_fullStr |
Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis |
title_full_unstemmed |
Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis |
title_sort |
changes in the lungs of a child with gaucher disease: differential diagnosis with disseminated tuberculosis |
publisher |
NEW TERRA Publishing House |
series |
Tuberkulez i Bolezni Lëgkih |
issn |
2075-1230 2542-1506 |
publishDate |
2020-11-01 |
description |
The article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomography. The particular parameter of latent tuberculosis infection of this case was the positive results of IGRA tests (T-SPOT TB and QuantiFERON) with a negative response to the intradermal test with recombinant tuberculosis allergen. According to the examination results, the disseminated tuberculosis was not confirmed, diffuse lung damage was regarded as a manifestation of Gaucher disease, which was a rare sign of this pathology according to the published data. |
topic |
children disseminated lung damage gaucher disease tuberculosis differential diagnosis |
url |
https://www.tibl-journal.com/jour/article/view/1474 |
work_keys_str_mv |
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