Changes in the lungs of a child with Gaucher disease: differential diagnosis with disseminated tuberculosis

• Main Authors: M. E. Lozovskaya, Yu. A. Yarovaya, E. В. Vasilieva, L. N. Khamchieva, A. V. Mosina, P. V. Gavrilov
• Format: Article
• Language: Russian
• Published: NEW TERRA Publishing House 2020-11-01
• Series: Tuberkulez i Bolezni Lëgkih
• Subjects: children; disseminated lung damage; gaucher disease; tuberculosis; differential diagnosis
• Online Access: https://www.tibl-journal.com/jour/article/view/1474

The article describes a clinical case of a rare combination of hereditary pathology – Gaucher disease and latent tuberculosis infection in an 8-year-old child. The child was examined for tuberculosis due to disseminated small foci and calcination in the lung tissue detected by chest computed tomography. The particular parameter of latent tuberculosis infection of this case was the positive results of IGRA tests (T-SPOT TB and QuantiFERON) with a negative response to the intradermal test with recombinant tuberculosis allergen. According to the examination results, the disseminated tuberculosis was not confirmed, diffuse lung damage was regarded as a manifestation of Gaucher disease, which was a rare sign of this pathology according to the published data.