Tissues Harvested Using an Automated Surgical Approach Confirm Molecular Heterogeneity of Glioblastoma and Enhance Specimen's Translational Research Value

Tissues Harvested Using an Automated Surgical Approach Confirm Molecular Heterogeneity of Glioblastoma and Enhance Specimen's Translational Research Value

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. Designing effective individualized therapies for GBM requires quality fresh tissue specimens, and a comprehensive molecular profile of this highly heterogenous neoplasm. Novel neuro-surgical approaches, such as the automated re...

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Bibliographic Details
Main Authors: Edie Zusman, Maxim Sidorov, Alexandria Ayala, Jimmin Chang, Eric Singer, Michelle Chen, Pierre-Yves Desprez, Sean McAllister, Nathan Salomonis, Kashish Chetal, Gautam Prasad, Tyler Kang, Joseph Mark, Lawrence Dickinson, Liliana Soroceanu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
PDX
tumor heterogeneity
Myriad
RNA seq
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01119/full

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