Functional polymorphisms of FAS and FASL gene and risk of breast cancer - pilot study of 134 cases.

Functional polymorphisms of FAS and FASL gene and risk of breast cancer - pilot study of 134 cases.

Fas/Fas ligand (FasL) system is one of the key apoptotic signaling entities in the extrinsic apoptotic pathway. De-regulation of this pathway, i.e. by mutations may prevent the immune system from the removal of newly-formed tumor cells, and thus lead to tumor formation. The present study investigate...

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Bibliographic Details
Main Authors: Mohammad Hashemi, Aliakbar Fazaeli, Saeid Ghavami, Ebrahim Eskandari-Nasab, Farshid Arbabi, Mohammad Ali Mashhadi, Mohsen Taheri, Wiem Chaabane, Mayur V Jain, Marek J Łos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23326385/?tool=EBI

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