Maternal exposure to high‐fat diet during pregnancy and lactation predisposes normal weight offspring mice to develop hepatic inflammation and insulin resistance

Maternal exposure to high‐fat diet during pregnancy and lactation predisposes normal weight offspring mice to develop hepatic inflammation and insulin resistance

Abstract Increasing evidence shows a potential link between the perinatal nutrient environment and metabolic outcome in offspring. Here, we investigated the effects of maternal feeding of a high‐fat diet (HFD) during the perinatal period on hepatic metabolism and inflammation in male offspring mice...

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Bibliographic Details
Main Authors: Suchaorn Saengnipanthkul, Hye Lim Noh, Randall H. Friedline, Sujin Suk, Stephanie Choi, Nicholas K. Acosta, Duy A. Tran, Xiaodi Hu, Kunikazu Inashima, Allison M. Kim, Ki Won Lee, Jason K. Kim
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Physiological Reports
Subjects:
high‐fat diet
inflammation
insulin resistance
lactation
liver
maternal nutrition
Online Access:https://doi.org/10.14814/phy2.14811

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