Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device

Background. Severe mitral regurgitation (MR) is common in patients who are undergoing insertion of a left ventricular assist device (LVAD). This study analyzes the outcomes of a transapical approach for edge-to-edge repair of the mitral valve during insertion of a left ventricular assist device in 1...

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Main Authors: Mark J. Russo, Aurelie Merlo, Elizabeth M. Johnson, Shahab Akhter, Sean McCarney, Jennifer Steiman, Allen Anderson, Valluvan Jeevanandam
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/925310
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spelling doaj-7e56454daddc411fb9c909b4e82e85162020-11-25T02:15:25ZengHindawi LimitedThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/925310925310Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist DeviceMark J. Russo0Aurelie Merlo1Elizabeth M. Johnson2Shahab Akhter3Sean McCarney4Jennifer Steiman5Allen Anderson6Valluvan Jeevanandam7Section of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USASection of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USASection of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USASection of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USASection of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USASection of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USASection of Cardiology, Department of Medicine, University of Chicago, Chicago, IL 60637, USASection of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USABackground. Severe mitral regurgitation (MR) is common in patients who are undergoing insertion of a left ventricular assist device (LVAD). This study analyzes the outcomes of a transapical approach for edge-to-edge repair of the mitral valve during insertion of a left ventricular assist device in 19 patients with MR. Methods. This retrospective study includes 19 patients who were implanted between March 21, 2011, and August 31, 2011, at the University of Chicago. Clinical data include preoperative ejection fraction, post- and preoperative pulmonary arterial pressures, cardiopulmonary bypass time, post- and preoperative mitral regurgitation severity, endotracheal CO2, and LVAD pulse index. Results. All of the 19 patients had a reduction in mitral regurgitation. Fourteen of the 19 patients had at least a three-point reduction in MR severity. The average postoperative pulmonary arterial pressure (PAP) decreased after the surgical procedure from 44/22 ± 14/5 mmHg to 57/28 ± 9/5 mmHg. Average CPB time was 128 ± 27 minutes. Average length-of-stay (LOS) was 21 ± 10 days. Conclusions. Concomitant MV repair using a transapical approach is advantageous for this small cohort of patients. The surgical procedure is less complex and has a shorter CPB time and LOS, and all of the patients demonstrated significant improvement in postoperative MR and moderate improvement in PAP.http://dx.doi.org/10.1155/2013/925310
collection DOAJ
language English
format Article
sources DOAJ
author Mark J. Russo
Aurelie Merlo
Elizabeth M. Johnson
Shahab Akhter
Sean McCarney
Jennifer Steiman
Allen Anderson
Valluvan Jeevanandam
spellingShingle Mark J. Russo
Aurelie Merlo
Elizabeth M. Johnson
Shahab Akhter
Sean McCarney
Jennifer Steiman
Allen Anderson
Valluvan Jeevanandam
Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device
The Scientific World Journal
author_facet Mark J. Russo
Aurelie Merlo
Elizabeth M. Johnson
Shahab Akhter
Sean McCarney
Jennifer Steiman
Allen Anderson
Valluvan Jeevanandam
author_sort Mark J. Russo
title Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device
title_short Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device
title_full Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device
title_fullStr Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device
title_full_unstemmed Transapical Approach for Mitral Valve Repair during Insertion of a Left Ventricular Assist Device
title_sort transapical approach for mitral valve repair during insertion of a left ventricular assist device
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2013-01-01
description Background. Severe mitral regurgitation (MR) is common in patients who are undergoing insertion of a left ventricular assist device (LVAD). This study analyzes the outcomes of a transapical approach for edge-to-edge repair of the mitral valve during insertion of a left ventricular assist device in 19 patients with MR. Methods. This retrospective study includes 19 patients who were implanted between March 21, 2011, and August 31, 2011, at the University of Chicago. Clinical data include preoperative ejection fraction, post- and preoperative pulmonary arterial pressures, cardiopulmonary bypass time, post- and preoperative mitral regurgitation severity, endotracheal CO2, and LVAD pulse index. Results. All of the 19 patients had a reduction in mitral regurgitation. Fourteen of the 19 patients had at least a three-point reduction in MR severity. The average postoperative pulmonary arterial pressure (PAP) decreased after the surgical procedure from 44/22 ± 14/5 mmHg to 57/28 ± 9/5 mmHg. Average CPB time was 128 ± 27 minutes. Average length-of-stay (LOS) was 21 ± 10 days. Conclusions. Concomitant MV repair using a transapical approach is advantageous for this small cohort of patients. The surgical procedure is less complex and has a shorter CPB time and LOS, and all of the patients demonstrated significant improvement in postoperative MR and moderate improvement in PAP.
url http://dx.doi.org/10.1155/2013/925310
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