Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton
Extracellular vesicles have been described in non-paracrine cellular interactions in cancer. We report a similar phenomenon in B-cell precursor (BCP) acute lymphoblastic leukaemia (ALL). Using advanced microscopy and high throughput screening, we further characterise a subset of large vesicles (LEVs...
Main Authors: | Suzanne M. Johnson, Clare Dempsey, Catriona Parker, Aleksandr Mironov, Helen Bradley, Vaskar Saha |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-12-01
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Series: | Journal of Extracellular Vesicles |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/20013078.2017.1294339 |
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