A very low geno2pheno false positive rate is associated with poor viro-immunological response in drug-naïve patients starting a first-line HAART.

<h4>Background</h4>We previously found that a very low geno2pheno false positive rate (FPR ≤ 2%) defines a viral population associated with low CD4 cell count and the highest amount of X4-quasispecies. In this study, we aimed at evaluating whether FPR ≤ 2% might impact on the viro-immuno...

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Main Authors: Daniele Armenia, Cathia Soulie, Domenico Di Carlo, Lavinia Fabeni, Caterina Gori, Federica Forbici, Valentina Svicher, Ada Bertoli, Loredana Sarmati, Massimo Giuliani, Alessandra Latini, Evangelo Boumis, Mauro Zaccarelli, Rita Bellagamba, Massimo Andreoni, Anne-Geneviève Marcelin, Vincent Calvez, Andrea Antinori, Francesca Ceccherini-Silberstein, Carlo-Federico Perno, Maria Mercedes Santoro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25153969/pdf/?tool=EBI