Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report
Kikuchi-Fujimoto disease is a self-limited benign condition of unknown etiology characterized by cervical lymphadenopathy, fever, and leucopenia. An autoimmune hypothesis has been suggested and an association with systemic lupus erythematosus, Sjogren's disease, and antiphospholipid syndrome ha...
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doaj-7e645ed32369428f8ad52a86419d97542020-11-24T22:26:35ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/903252903252Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case ReportOlukayode Onasanya0David Nochlin1Victor Casas2Leema Reddy Peddareddygari3Raji P. Grewal4Laboratory of Neurogenetics, New Jersey Neuroscience Institute, JFK Medical Center, 65 James Street, Edison NJ, 08820, USALaboratory of Neurogenetics, New Jersey Neuroscience Institute, JFK Medical Center, 65 James Street, Edison NJ, 08820, USALaboratory of Neurogenetics, New Jersey Neuroscience Institute, JFK Medical Center, 65 James Street, Edison NJ, 08820, USALaboratory of Neurogenetics, New Jersey Neuroscience Institute, JFK Medical Center, 65 James Street, Edison NJ, 08820, USALaboratory of Neurogenetics, New Jersey Neuroscience Institute, JFK Medical Center, 65 James Street, Edison NJ, 08820, USAKikuchi-Fujimoto disease is a self-limited benign condition of unknown etiology characterized by cervical lymphadenopathy, fever, and leucopenia. An autoimmune hypothesis has been suggested and an association with systemic lupus erythematosus, Sjogren's disease, and antiphospholipid syndrome has been noted. We report a 27-year-old male who presented for evaluation of weakness and he was diagnosed with seropositive generalized myasthenia gravis and underwent a thymectomy. He was stable until five months post-thymectomy, when he developed a high fever associated with nontender cervical lymphadenopathy, chills, and night sweats. Histopathology of a cervical lymph gland biopsy was compatible with Kikuchi-Fujimoto lymphadenitis. He improved spontaneously and was asymptomatic at the followup six months later. Our case expands the association of Kikuchi-Fujimoto disease with autoimmune disorders to include myasthenia gravis.http://dx.doi.org/10.1155/2010/903252 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Olukayode Onasanya David Nochlin Victor Casas Leema Reddy Peddareddygari Raji P. Grewal |
spellingShingle |
Olukayode Onasanya David Nochlin Victor Casas Leema Reddy Peddareddygari Raji P. Grewal Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report Case Reports in Medicine |
author_facet |
Olukayode Onasanya David Nochlin Victor Casas Leema Reddy Peddareddygari Raji P. Grewal |
author_sort |
Olukayode Onasanya |
title |
Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report |
title_short |
Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report |
title_full |
Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report |
title_fullStr |
Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report |
title_full_unstemmed |
Kikuchi-Fujimoto Disease Associated with Myasthenia Gravis: A Case Report |
title_sort |
kikuchi-fujimoto disease associated with myasthenia gravis: a case report |
publisher |
Hindawi Limited |
series |
Case Reports in Medicine |
issn |
1687-9627 1687-9635 |
publishDate |
2010-01-01 |
description |
Kikuchi-Fujimoto disease is a self-limited benign condition of unknown etiology characterized by cervical lymphadenopathy, fever, and leucopenia. An autoimmune hypothesis has been suggested and an association with systemic lupus erythematosus, Sjogren's disease, and antiphospholipid syndrome has been noted. We report a 27-year-old male who presented for evaluation of weakness and he was diagnosed with seropositive generalized myasthenia gravis and underwent a thymectomy. He was stable until five months post-thymectomy, when he developed a high fever associated with nontender cervical lymphadenopathy, chills, and night sweats. Histopathology of a cervical lymph gland biopsy was compatible with Kikuchi-Fujimoto lymphadenitis. He improved spontaneously and was asymptomatic at the followup six months later. Our case expands the association of Kikuchi-Fujimoto disease with autoimmune disorders to include myasthenia gravis. |
url |
http://dx.doi.org/10.1155/2010/903252 |
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