Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa

Pseudomonas aeruginosa is a dangerous opportunistic pathogen. One of the most negative clinically significant features of P. aeruginosa is associated with the rapid acquisition of antimicrobial resistance. This review provides an analysis of current literature data on genetic mechanisms of resistanc...

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Main Authors: Chebotar I.V., Bocharova Yu.A., Mayansky N.A.
Format: Article
Language:Russian
Published: Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy 2017-11-01
Series:Клиническая микробиология и антимикробная химиотерапия
Subjects:
Online Access:https://cmac-journal.ru/publication/2017/4/cmac-2017-t19-n4-p308/cmac-2017-t19-n4-p308.pdf
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spelling doaj-7e7a51cead644c478c43152aa7566c6b2020-11-25T02:06:54ZrusInterregional Association for Clinical Microbiology and Antimicrobial ChemotherapyКлиническая микробиология и антимикробная химиотерапия1684-43862686-95862017-11-01194308319cmac-2017-t19-n4-p308Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosaChebotar I.V.0Bocharova Yu.A.1Mayansky N.A.2National Medical Research Center of Children’s Health, Moscow, RussiaNational Medical Research Center of Children’s Health, Moscow, RussiaNational Medical Research Center of Children’s Health, Moscow, RussiaPseudomonas aeruginosa is a dangerous opportunistic pathogen. One of the most negative clinically significant features of P. aeruginosa is associated with the rapid acquisition of antimicrobial resistance. This review provides an analysis of current literature data on genetic mechanisms of resistance of P. aeruginosa to antibiotics. Acquisition of resistance and its regulation are considered. Understanding of resistance mechanisms and regulation is an important basis to ensure appropriate antimicrobial therapy and infection control measures in patients with pseudomonas infections.https://cmac-journal.ru/publication/2017/4/cmac-2017-t19-n4-p308/cmac-2017-t19-n4-p308.pdfpseudomonas aeruginosaantibioticsresistancebeta-lactamasespermeabilityefflux
collection DOAJ
language Russian
format Article
sources DOAJ
author Chebotar I.V.
Bocharova Yu.A.
Mayansky N.A.
spellingShingle Chebotar I.V.
Bocharova Yu.A.
Mayansky N.A.
Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa
Клиническая микробиология и антимикробная химиотерапия
pseudomonas aeruginosa
antibiotics
resistance
beta-lactamases
permeability
efflux
author_facet Chebotar I.V.
Bocharova Yu.A.
Mayansky N.A.
author_sort Chebotar I.V.
title Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa
title_short Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa
title_full Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa
title_fullStr Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa
title_full_unstemmed Mechanisms and regulation of antimicrobial resistance in Pseudomonas aeruginosa
title_sort mechanisms and regulation of antimicrobial resistance in pseudomonas aeruginosa
publisher Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy
series Клиническая микробиология и антимикробная химиотерапия
issn 1684-4386
2686-9586
publishDate 2017-11-01
description Pseudomonas aeruginosa is a dangerous opportunistic pathogen. One of the most negative clinically significant features of P. aeruginosa is associated with the rapid acquisition of antimicrobial resistance. This review provides an analysis of current literature data on genetic mechanisms of resistance of P. aeruginosa to antibiotics. Acquisition of resistance and its regulation are considered. Understanding of resistance mechanisms and regulation is an important basis to ensure appropriate antimicrobial therapy and infection control measures in patients with pseudomonas infections.
topic pseudomonas aeruginosa
antibiotics
resistance
beta-lactamases
permeability
efflux
url https://cmac-journal.ru/publication/2017/4/cmac-2017-t19-n4-p308/cmac-2017-t19-n4-p308.pdf
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