Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis

CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+CD57+ T cells in a young patient...

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Main Authors:	R. García-Muñoz, P. Rodríguez-Otero, A. Galar, J. Merino, J. J. Beunza, J. A. Páramo, R. Lecumberri
Format:	Article
Language:	English
Published:	Hindawi Limited 2009-01-01
Series:	Advances in Hematology
Online Access:	http://dx.doi.org/10.1155/2009/173439

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spelling	doaj-7e85a0ffbe4544fbaea88fc72ee529db2021-07-02T02:39:44ZengHindawi LimitedAdvances in Hematology1687-91041687-91122009-01-01200910.1155/2009/173439173439Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute ToxoplasmosisR. García-Muñoz0P. Rodríguez-Otero1A. Galar2J. Merino3J. J. Beunza4J. A. Páramo5R. Lecumberri6Department of Hematology, Hospital San Pedro, Logroño, La Rioja 26006, SpainDepartment of Hematology, University Clinic, University of Navarra, 31008 Navarra, SpainDepartment of Microbiology, University Clinic, University of Navarra, 31008 Navarra, SpainDepartment of Immunology, University Clinic, University of Navarra, 31008 Navarra, SpainDepartment of Preventive Medicine and Public Health, University of Navarra, 31008 Navarra, SpainDepartment of Hematology, University Clinic, University of Navarra, 31008 Navarra, SpainDepartment of Hematology, University Clinic, University of Navarra, 31008 Navarra, SpainCD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+CD57+ T cells in a young patient with an acute infection with Toxoplasma gondii. Our report supports the concept that CD8+CD57+ T cells could be important in the control of chronic phase of intracellular microorganisms and that the high numbers of these cells may reflect the continuing survey of the immune system, searching for parasite proliferation in the tissues.http://dx.doi.org/10.1155/2009/173439
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	R. García-Muñoz P. Rodríguez-Otero A. Galar J. Merino J. J. Beunza J. A. Páramo R. Lecumberri
spellingShingle	R. García-Muñoz P. Rodríguez-Otero A. Galar J. Merino J. J. Beunza J. A. Páramo R. Lecumberri Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis Advances in Hematology
author_facet	R. García-Muñoz P. Rodríguez-Otero A. Galar J. Merino J. J. Beunza J. A. Páramo R. Lecumberri
author_sort	R. García-Muñoz
title	Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_short	Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_full	Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_fullStr	Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_full_unstemmed	Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_sort	expansion of cd8+cd57+ t cells in an immunocompetent patient with acute toxoplasmosis
publisher	Hindawi Limited
series	Advances in Hematology
issn	1687-9104 1687-9112
publishDate	2009-01-01
description	CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+CD57+ T cells in a young patient with an acute infection with Toxoplasma gondii. Our report supports the concept that CD8+CD57+ T cells could be important in the control of chronic phase of intracellular microorganisms and that the high numbers of these cells may reflect the continuing survey of the immune system, searching for parasite proliferation in the tissues.
url	http://dx.doi.org/10.1155/2009/173439
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Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis

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