Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece
Introduction: Prostatic multiparametric magnetic resonance (mpMRI) allows for guided prostate biopsy (PB). Objective: To evaluate localization agreement between mpMRI lesions and histology obtained by cognitive PB and radical prostatectomy (RP) surgical specimen (SS). Methods: Out of 115 consecuti...
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doaj-7e8b780a0a4d42db8d07c619ca249a422020-11-25T03:19:38ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972020-01-0191410.4081/aiua.2019.4.218Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy pieceMario Lourenço0Pedro Pissarra1Duarte Vieira e Brito2Miguel Eliseu3Joao Pedro Peralta4Arnaldo Figueiredo5Cristina Marques6Urology department Portuguese Institute of Oncology CoimbraRadiology Department Coimbra Hospital University Centre, CoimbraUrology Department Portuguese Institute of Oncology Coimbra, CoimbraUrology and Kidney Transplant Department Coimbra Hospital University Centre, CoimbraUrology Department Portuguese Institute of Oncology Coimbra, CoimbraUrology and Kidney Transplant Department Coimbra Hospital University Centre, CoimbraRadiology Department Coimbra Hospital University Centre, Coimbra Introduction: Prostatic multiparametric magnetic resonance (mpMRI) allows for guided prostate biopsy (PB). Objective: To evaluate localization agreement between mpMRI lesions and histology obtained by cognitive PB and radical prostatectomy (RP) surgical specimen (SS). Methods: Out of 115 consecutive cognitive biopsied patients, 37 with positive PB were studied. Sample was characterized regarding age, prostatic volume, PI-RADS, location of lesion on mpMRI, lesion dimension, total number of fragments obtain by PB, number of fragments directed to the lesion, number of fragments with prostatic adenocarcinoma (PCa) and ISUP classification. The relationship between mpMRI and SS piece was analysed in 15 patients who underwent RP. Results: Regarding agreement between mpMRI and PB, agreement of location was observed in 26 (70.3%); 7 (18.9%) presented PCa positive fragments in the suspected zone plus others in the same lobe; 3 (8.1%) in the suspected zone plus the contralateral lobe and 1 (2.7%) had no PCa in the suspected zone but had bilateral PCa. The total number of fragments with PCa was lower in cases with agreement between mpMRI and PB (p < 0.05). Regarding agreement between mpMRI and SS, 5 cases (33.3%) presented the same location as described by mpMRI, 5 (33.3%) showed ipsilateral lesions in other zones of the prostate; 4 (26.7%) presented extensive bilateral lesions on all prostate zones and 1 (6.7%) showed previously unknown contralateral lesions. None of the factors studied related mpMRI and RP (p > 0.05). Conclusions: Localization agreement of mpMRI vs PB and mpMRI vs SS was present in 26/37 (70.3%) and 5/15 (33.3%), respectively. That suggests the existence of other lesions (multifocality) not identified on mpMRI. https://pagepressjournals.org/index.php/aiua/article/view/8332prostate biopsycognitive prostate biopsymultiparametric magnetic resonance imagingprostate cancerlocalization agreementmultifocality |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mario Lourenço Pedro Pissarra Duarte Vieira e Brito Miguel Eliseu Joao Pedro Peralta Arnaldo Figueiredo Cristina Marques |
spellingShingle |
Mario Lourenço Pedro Pissarra Duarte Vieira e Brito Miguel Eliseu Joao Pedro Peralta Arnaldo Figueiredo Cristina Marques Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece Archivio Italiano di Urologia e Andrologia prostate biopsy cognitive prostate biopsy multiparametric magnetic resonance imaging prostate cancer localization agreement multifocality |
author_facet |
Mario Lourenço Pedro Pissarra Duarte Vieira e Brito Miguel Eliseu Joao Pedro Peralta Arnaldo Figueiredo Cristina Marques |
author_sort |
Mario Lourenço |
title |
Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece |
title_short |
Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece |
title_full |
Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece |
title_fullStr |
Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece |
title_full_unstemmed |
Lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece |
title_sort |
lesion location agreement between prostatic multiparametric magnetic resonance, cognitive fusion biopsy and radical prostatectomy piece |
publisher |
PAGEPress Publications |
series |
Archivio Italiano di Urologia e Andrologia |
issn |
1124-3562 2282-4197 |
publishDate |
2020-01-01 |
description |
Introduction: Prostatic multiparametric magnetic resonance (mpMRI) allows for guided prostate biopsy (PB).
Objective: To evaluate localization agreement between mpMRI lesions and histology obtained by cognitive PB and radical prostatectomy (RP) surgical specimen (SS).
Methods: Out of 115 consecutive cognitive biopsied patients, 37 with positive PB were studied. Sample was characterized regarding age, prostatic volume, PI-RADS, location of lesion on mpMRI, lesion dimension, total number of fragments obtain by PB, number of fragments directed to the lesion, number of fragments with prostatic adenocarcinoma (PCa) and ISUP classification. The relationship between mpMRI and SS piece was analysed in 15 patients who underwent RP.
Results: Regarding agreement between mpMRI and PB, agreement of location was observed in 26 (70.3%); 7 (18.9%) presented PCa positive fragments in the suspected zone plus others in the same lobe; 3 (8.1%) in the suspected zone plus the contralateral lobe and 1 (2.7%) had no PCa in the suspected zone but had bilateral PCa. The total number of fragments with PCa was lower in cases with agreement between mpMRI and PB (p < 0.05). Regarding agreement between mpMRI and SS, 5 cases (33.3%) presented the same location as described by mpMRI, 5 (33.3%) showed ipsilateral lesions in other zones of the prostate; 4 (26.7%) presented extensive bilateral lesions on all prostate zones and 1 (6.7%) showed previously unknown contralateral lesions. None of the factors studied related mpMRI and RP (p > 0.05).
Conclusions: Localization agreement of mpMRI vs PB and mpMRI vs SS was present in 26/37 (70.3%) and 5/15 (33.3%), respectively. That suggests the existence of other lesions (multifocality) not identified on mpMRI.
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topic |
prostate biopsy cognitive prostate biopsy multiparametric magnetic resonance imaging prostate cancer localization agreement multifocality |
url |
https://pagepressjournals.org/index.php/aiua/article/view/8332 |
work_keys_str_mv |
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